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Abrilada (Adalimumab)
Out Of Stock
General Medication Fact Sheet for Abrilada
| Field | Information |
|---|---|
| Medication Name | Abrilada |
| Generic Name | Adalimumab-adaz |
| Boxed/Label Warning | Serious infections and malignancies. See full prescribing information for details. |
| Purpose | Biosimilar to Humira used to treat autoimmune diseases such as rheumatoid arthritis, Crohn’s disease, ulcerative colitis, plaque psoriasis, ankylosing spondylitis, and others. |
| Mechanism of Action | A tumor necrosis factor (TNF) blocker that works by blocking the activity of TNF-alpha, a protein in the body that causes inflammation. |
| Dosage Forms | Subcutaneous injection |
| Available Strengths | 40 mg/0.8 mL |
| Dosage Frequency | Varies by condition, typically every other week or weekly. Follow your doctor’s instructions. |
| Common Side Effects | Injection site reactions (pain, swelling, redness), headache, rash |
| Serious Side Effects | Serious infections (tuberculosis, fungal infections), lymphoma, other cancers, allergic reactions, nervous system disorders, blood disorders, heart failure, liver problems |
| Drug Interactions | Other TNF blockers (e.g., etanercept, infliximab), anakinra, abatacept, live vaccines, methotrexate, azathioprine |
| Important Notes | Before starting, get tested for TB and other infections. Monitor for signs of infection. Do not receive live vaccines while taking this medication. |
| Storage | Store in the refrigerator. Do not freeze. Protect from light. |
| Missed Dose | Inject the missed dose as soon as you remember. Then, take your next dose at your regular scheduled time. |
| Alternatives | Humira (adalimumab), Enbrel (etanercept), Remicade (infliximab), Cimzia (certolizumab pegol), Simponi (golimumab) |
Abrilada Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Humira (adalimumab) | TNF-alpha inhibitor | The original brand-name adalimumab product. |
| Enbrel (etanercept) | TNF-alpha inhibitor | Another TNF-alpha inhibitor used for similar conditions. |
| Remicade (infliximab) | TNF-alpha inhibitor | Administered via intravenous infusion. |
| Cimzia (certolizumab pegol) | TNF-alpha inhibitor | Pegylated TNF-alpha inhibitor, potentially offering longer duration of action. |
Abrilada Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Injection site reactions (pain, swelling, redness) | Serious infections (tuberculosis, fungal infections, bacterial infections) |
| Headache | Lymphoma and other cancers |
| Rash | Allergic reactions (hives, difficulty breathing, swelling of the face/throat) |
| Upper respiratory infections (sinus infections, common cold) | Nervous system disorders (multiple sclerosis, optic neuritis, seizures) |
| Nausea | Blood disorders (anemia, leukopenia, thrombocytopenia) |
Abrilada Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Rheumatoid Arthritis | 40 mg every other week | 40 mg every other week | May be given weekly if not on methotrexate. Administer via subcutaneous injection. |
| Crohn’s Disease | 160 mg initially, then 80 mg two weeks later | 40 mg every other week | Administer via subcutaneous injection. Dosage may vary depending on individual response. |
| Ulcerative Colitis | 160 mg initially, then 80 mg two weeks later | 40 mg every other week | Administer via subcutaneous injection. Dosage may vary depending on individual response. |
| Plaque Psoriasis | 80 mg initially | 40 mg every other week | Administer via subcutaneous injection. |
| Ankylosing Spondylitis | 40 mg every other week | 40 mg every other week | Administer via subcutaneous injection. |
Abrilada Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance (Pfizer enCompass co-pay assistance program) | $0 |
| Without Insurance (U.S.) | $6,738.47 |
| From Canada | $1484.50 |
