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Acebutolol (Generic)
| Sectral Acebutolol Hydrochloride | ||||||
Shipped from United Kingdom | ||||||
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| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
General Medication Fact Sheet for Acebutolol
| Field | Information |
|---|---|
| Generic Name | Acebutolol |
| Brand Name Versions | Sectral |
| Boxed/Label Warning | Do not stop taking acebutolol suddenly, especially if you have heart disease. Abruptly stopping this medication can worsen chest pain (angina) or lead to a heart attack. Your doctor will likely decrease your dose gradually over 1 to 2 weeks before stopping it completely. |
| Purpose | Used to treat high blood pressure (hypertension), chest pain (angina pectoris), and certain heart rhythm disorders (ventricular arrhythmias). |
| Mechanism of Action | A beta-1 selective adrenergic blocker that works by blocking beta-1 receptors, primarily in the heart, to reduce heart rate, contractility, and blood pressure. It also possesses intrinsic sympathomimetic activity (ISA). |
| Dosage Forms | Oral capsules |
| Available Strengths | 200 mg, 400 mg |
| Dosage Frequency | Typically once or twice daily, as directed by a healthcare provider. |
| Common Side Effects | Fatigue, dizziness, headache, slow heart rate (bradycardia), digestive upset (nausea, constipation, diarrhea), difficulty sleeping. |
| Serious Side Effects | Severe slow heart rate, worsening heart failure symptoms (shortness of breath, swelling, weight gain), bronchospasm (difficulty breathing), masking symptoms of low blood sugar in diabetics, cold hands or feet, depression, sexual dysfunction. |
| Drug Interactions | May interact with other blood pressure medications (e.g., calcium channel blockers, ACE inhibitors, ARBs), other heart rate lowering drugs (e.g., digoxin, amiodarone), NSAIDs, certain antidepressants, and epinephrine. Always inform your doctor about all medications, supplements, and herbal products you are taking. |
| Important Notes | Do not stop taking this medication without consulting your doctor. Use caution in patients with asthma, COPD, diabetes, liver or kidney problems. May affect alertness; avoid driving or operating machinery if dizzy. |
| Storage | Store at room temperature (typically 68°F to 77°F or 20°C to 25°C) away from moisture and light. Keep out of reach of children. |
| Missed Dose | If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. |
| Alternatives | Metoprolol, Atenolol, Propranolol, Amlodipine, Lisinopril |
Acebutolol Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Metoprolol (Lopressor, Toprol XL) | Beta-1 selective blocker | A widely used beta-blocker for hypertension, angina, and heart failure. Available in immediate and extended-release forms. |
| Atenolol (Tenormin) | Beta-1 selective blocker | Similar uses to acebutolol and Metoprolol, often dosed once daily. Primarily excreted by the kidneys. |
| Propranolol (Inderal) | Non-selective beta blocker | Used for hypertension, angina, arrhythmias, migraine prophylaxis, and performance anxiety. Affects both beta-1 and beta-2 receptors. |
| Amlodipine (Norvasc) | Calcium channel blocker | Used for hypertension and angina. Works by relaxing blood vessels. Often used in combination therapy. |
| Lisinopril (Zestril, Prinivil) | ACE inhibitor | Used for hypertension, heart failure, and post-MI. Works by blocking a substance that narrows blood vessels. |
Acebutolol Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Fatigue | Severe slow heart rate (bradycardia) |
| Dizziness | Worsening heart failure (shortness of breath, swelling, weight gain) |
| Headache | Bronchospasm (difficulty breathing) |
| Slow heart rate (bradycardia) | Masking symptoms of low blood sugar in diabetics |
| Nausea | Cold hands or feet (Raynaud’s phenomenon) |
| Constipation | Depression |
| Diarrhea | Sexual dysfunction |
| Difficulty sleeping | Severe allergic reactions (rash, itching, swelling, trouble breathing) |
Acebutolol Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hypertension | 200-400 mg once or twice daily | 400-800 mg per day, typically divided into two doses | Doses up to 1200 mg/day have been used, but higher doses may lose cardioselectivity. |
| Angina Pectoris | 200-400 mg twice daily | 400-800 mg per day, divided into two doses | Some patients may require up to 1200 mg/day. |
| Ventricular Arrhythmias | 200 mg twice daily | 400-1200 mg per day, divided into two doses | Dosage should be adjusted based on patient response and tolerance, with cardiac monitoring. |
Acebutolol Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $4 |
| Without Insurance (U.S.) | $131.29 |
| From Canada | $29.40 |

