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Apriso (Mesalamine)
| 5-ASA (Generic) Mesalamine | ||||||
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Shipped from Canada | ||||||
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| Mesacol (Generic) Mesalamine | ||||||
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Shipped from Mauritius | ||||||
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Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Mesalamine (Generic) Mesalamine | ||||||
|
Shipped from Mauritius | ||||||
| | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
General Medication Fact Sheet for Apriso
| Field | Information |
|---|---|
| Medication Name | Apriso |
| Generic Name | Mesalamine |
| Boxed/Label Warning | Rarely, acute intolerance syndrome mimicking infectious colitis. |
| Purpose | Treatment of ulcerative colitis to reduce inflammation in the colon |
| Mechanism of Action | Thought to work by reducing inflammation in the colon by blocking the production of substances that cause inflammation. The specific mechanism is not fully understood. |
| Dosage Forms | Extended-release capsules |
| Available Strengths | 0.375 g |
| Dosage Frequency | Four capsules (1.5g) once daily, in the morning. |
| Common Side Effects | Headache, flatulence, abdominal pain, nausea |
| Serious Side Effects | Worsening of colitis symptoms, kidney problems, liver problems, allergic reactions (rash, itching, swelling, difficulty breathing), heart problems (myocarditis, pericarditis) |
| Drug Interactions | Azathioprine, 6-mercaptopurine, NSAIDs (e.g., ibuprofen, naproxen), vaccines |
| Important Notes | Swallow the capsules whole; do not crush, chew, or break them. Drink plenty of fluids while taking this medication. Contact your doctor if you experience worsening of colitis symptoms. |
| Storage | Store at room temperature away from moisture and light. Keep out of reach of children. |
| Missed Dose | Take as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. |
| Alternatives | Asacol HD (mesalamine), Lialda (mesalamine), Sulfasalazine, Balsalazide |
Apriso Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Asacol HD (mesalamine) | Aminosalicylate; thought to reduce inflammation in the colon. | Delayed-release tablet formulation. |
| Lialda (mesalamine) | Aminosalicylate; thought to reduce inflammation in the colon. | Extended-release tablet formulation. |
| Sulfasalazine | Aminosalicylate and antibacterial properties; reduces inflammation. | Older medication, often less expensive but with more potential side effects. |
| Balsalazide | Aminosalicylate; reduces inflammation in the colon. | Prodrug of mesalamine, activated in the colon. |
Apriso Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Worsening of colitis symptoms |
| Flatulence | Kidney problems |
| Abdominal pain | Liver problems |
| Nausea | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Diarrhea | Heart problems (myocarditis, pericarditis) |
Apriso Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Ulcerative Colitis | 1.5 g (4 capsules) once daily | 1.5 g (4 capsules) once daily | Take in the morning. Swallow whole, do not crush or chew. |
