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General Medication Fact Sheet for Biktarvy
| Field | Information |
|---|---|
| Medication Name | Biktarvy |
| Generic Name | Bictegravir/Emtricitabine/Tenofovir Alafenamide |
| Boxed/Label Warning | Post treatment acute exacerbation of hepatitis B. All patients should be tested for hepatitis B virus (HBV) before or when initiating Biktarvy. |
| Purpose | Complete treatment regimen for Human Immunodeficiency Virus Type 1 (HIV-1) infection. |
| Mechanism of Action | Inhibits HIV-1 integrase (bictegravir) and reverse transcriptase (emtricitabine and tenofovir alafenamide), blocking viral replication. |
| Dosage Forms | Oral tablets |
| Available Strengths | 50 mg bictegravir/200 mg emtricitabine/25 mg tenofovir alafenamide |
| Dosage Frequency | Once daily |
| Common Side Effects | Diarrhea, nausea, headache, fatigue, abnormal dreams, dizziness |
| Serious Side Effects | New or worsening kidney problems, liver problems, bone problems, changes in immune system (immune reconstitution syndrome), lactic acidosis |
| Drug Interactions | Antacids containing magnesium or aluminum, calcium supplements, iron supplements, rifampin, certain anticonvulsants. Consult your pharmacist or healthcare provider for a complete list. |
| Important Notes | Biktarvy is a complete HIV-1 regimen. Do not take with other HIV-1 medications. Consult with your healthcare provider before starting any new medications or supplements. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember if it is within 18 hours of your normal time. If it is more than 18 hours, skip the dose and continue with your regular dosing schedule. Do not double the dose. |
| Alternatives | Triumeq (abacavir/dolutegravir/lamivudine), Dovato (dolutegravir/lamivudine), Tivicay (dolutegravir) + Descovy (emtricitabine/tenofovir alafenamide) |
Biktarvy Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Triumeq (abacavir/dolutegravir/lamivudine) | Integrase inhibitor and nucleoside reverse transcriptase inhibitors (NRTIs) | Complete regimen; contains abacavir, so genetic testing required. |
| Dovato (dolutegravir/lamivudine) | Integrase inhibitor and NRTI | Complete regimen; not recommended if HIV viral load is high. |
| Tivicay (dolutegravir) + Descovy (emtricitabine/tenofovir alafenamide) | Integrase inhibitor + NRTIs | Two-pill regimen; requires both medications to be taken together. |
Biktarvy Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Diarrhea | New or worsening kidney problems |
| Nausea | Liver problems |
| Headache | Bone problems |
| Fatigue | Changes in immune system (immune reconstitution syndrome) |
| Abnormal dreams | Lactic acidosis (rare but serious) |
| Dizziness | Depression or mood changes |
Biktarvy Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| HIV-1 Infection (Adults) | One tablet daily | One tablet daily | Take with or without food. |
| HIV-1 Infection (Adolescents weighing at least 25 kg) | One tablet daily | One tablet daily | Take with or without food. |
Biktarvy Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $100 – $150 |
| Without Insurance (U.S.) | $7,797 |
| From Canada | $1549.95 |
