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General Medication Fact Sheet for Bonviva
| Field | Information |
|---|---|
| Medication Name | Bonviva |
| Generic Name | Ibandronate Sodium |
| Boxed/Label Warning | Rare reports of atypical femur fractures and osteonecrosis of the jaw. |
| Purpose | Treatment and prevention of osteoporosis in postmenopausal women. |
| Mechanism of Action | Inhibits osteoclast activity, reducing bone resorption. |
| Dosage Forms | Oral tablet, intravenous injection |
| Available Strengths | 150 mg (oral), 3 mg/3 mL (IV) |
| Dosage Frequency | 150 mg once monthly (oral) or 3 mg every 3 months (IV). |
| Common Side Effects | Heartburn, indigestion, bone/muscle/joint pain, headache, flu-like symptoms. |
| Serious Side Effects | Osteonecrosis of the jaw, atypical femur fractures, esophageal problems, hypocalcemia, severe bone/joint/muscle pain. |
| Drug Interactions | Calcium supplements, antacids, iron supplements (take at different times of day), aspirin, NSAIDs. |
| Important Notes | Take oral tablet on an empty stomach, at least 60 minutes before the first food or drink of the day. Stay upright for 60 minutes after taking the tablet. Ensure adequate calcium and vitamin D intake. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | If you miss a monthly dose, take the tablet the morning after you remember, unless your next scheduled dose is within 7 days. If your next dose is within 7 days, skip the missed dose and take the next dose on the regularly scheduled day. Do not take two tablets within the same week. For IV, consult your doctor. |
| Alternatives | Fosamax (alendronate), Actonel (risedronate), Reclast (zoledronic acid), Prolia (denosumab). |
Bonviva Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Fosamax (alendronate) | Inhibits osteoclast-mediated bone resorption | Oral bisphosphonate taken daily or weekly. |
| Actonel (risedronate) | Inhibits osteoclast-mediated bone resorption | Oral bisphosphonate taken daily, weekly, or monthly. |
| Reclast (zoledronic acid) | Inhibits osteoclast-mediated bone resorption | Intravenous bisphosphonate administered once yearly. |
| Prolia (denosumab) | RANKL inhibitor, reduces osteoclast formation | Subcutaneous injection administered every 6 months. |
Bonviva Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Heartburn | Osteonecrosis of the jaw |
| Indigestion | Atypical femur fractures |
| Bone/muscle/joint pain | Esophageal problems (heartburn, difficulty swallowing, pain when swallowing) |
| Headache | Hypocalcemia (muscle spasms, numbness, tingling) |
| Flu-like symptoms | Severe bone/joint/muscle pain |
Bonviva Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Osteoporosis Treatment (Oral) | 150 mg | 150 mg once monthly | Take on an empty stomach, at least 60 minutes before food/drink. Stay upright for 60 minutes. |
| Osteoporosis Prevention (Oral) | 150 mg | 150 mg once monthly | Take on an empty stomach, at least 60 minutes before food/drink. Stay upright for 60 minutes. |
| Osteoporosis Treatment (IV) | 3 mg | 3 mg every 3 months | Administered by a healthcare professional. Ensure adequate hydration. |
Bonviva Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10–$5 |
| Without Insurance (U.S.) | $180–$220 |
