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General Medication Fact Sheet for Buccastem
| Field | Information |
|---|---|
| Medication Name | Buccastem |
| Generic Name | Prochlorperazine |
| Boxed/Label Warning | Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Buccastem is not approved for treating dementia-related psychosis. |
| Purpose | Antiemetic used to relieve nausea and vomiting |
| Mechanism of Action | Blocks dopamine receptors in the brain, reducing nausea signals |
| Dosage Forms | Buccal tablets |
| Available Strengths | 3 mg |
| Dosage Frequency | Typically one tablet twice daily as needed, up to a maximum of two tablets per day |
| Common Side Effects | Drowsiness, dry mouth, blurred vision, constipation |
| Serious Side Effects | Neuroleptic malignant syndrome (NMS), tardive dyskinesia, extrapyramidal symptoms (EPS), seizures |
| Drug Interactions | Other central nervous system depressants (e.g., alcohol, sedatives), anticholinergics, dopamine agonists |
| Important Notes | Avoid alcohol while taking this medication; use caution when driving or operating machinery; consult a doctor if you experience involuntary muscle movements |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember, unless it’s almost time for your next dose. Do not take two doses at once. |
| Alternatives | Ondansetron (Zofran), Promethazine (Phenergan), Metoclopramide (Reglan), Dimenhydrinate (Dramamine) |
Buccastem Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Ondansetron (Zofran) | Serotonin 5-HT3 receptor antagonist | Commonly used for chemotherapy-induced nausea and vomiting. |
| Promethazine (Phenergan) | Histamine H1 receptor antagonist, dopamine D2 receptor antagonist | May cause significant drowsiness. |
| Metoclopramide (Reglan) | Dopamine D2 receptor antagonist, increases GI motility | Can increase stomach emptying. |
| Dimenhydrinate (Dramamine) | Histamine H1 receptor antagonist | Available over-the-counter; useful for motion sickness. |
Buccastem Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Drowsiness | Neuroleptic malignant syndrome (NMS) |
| Dry mouth | Tardive dyskinesia |
| Blurred vision | Extrapyramidal symptoms (EPS) – muscle spasms, restlessness |
| Constipation | Seizures |
| Dizziness | Irregular heartbeat |
Buccastem Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Nausea and Vomiting | 3 mg | 3 mg twice daily as needed | Place tablet between cheek and gum and allow it to dissolve slowly. Do not chew or swallow whole. Max of 2 tablets per day. |
Buccastem Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 |
| Without Insurance (U.S.) | $50 |
