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General Medication Fact Sheet for Carvedilol
| Field | Information |
|---|---|
| Generic Name | Carvedilol |
| Brand Name Versions | Coreg, Coreg CR |
| Boxed/Label Warning | Abrupt cessation of therapy can cause exacerbation of angina and ventricular arrhythmias in patients with coronary artery disease. Dosage should be reduced gradually over 1 to 2 weeks. |
| Purpose | Used to treat high blood pressure and heart failure, and to reduce the risk of death after a heart attack. |
| Mechanism of Action | Alpha and beta-adrenergic receptor blocker. |
| Dosage Forms | Oral tablets, Extended-release capsules |
| Available Strengths | 3.125 mg, 6.25 mg, 12.5 mg, 25 mg, 80mg (CR) |
| Dosage Frequency | Twice daily (immediate-release), Once daily (extended-release) |
| Common Side Effects | Dizziness, fatigue, diarrhea, weakness, hypotension, bradycardia |
| Serious Side Effects | Worsening heart failure, severe hypotension, bronchospasm, heart block |
| Drug Interactions | Digoxin, calcium channel blockers (e.g., verapamil, diltiazem), insulin, oral diabetes medications, other blood pressure medications |
| Important Notes | Avoid abrupt discontinuation. May cause dizziness; use caution when driving or operating machinery. Consult a doctor if you have asthma or COPD. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Metoprolol, Bisoprolol, Atenolol, Lisinopril, Losartan |
Carvedilol Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Metoprolol (Lopressor, Toprol XL) | Selective beta-1 adrenergic blocker | Commonly used for high blood pressure and heart conditions. |
| Bisoprolol (Zebeta) | Selective beta-1 adrenergic blocker | Used for high blood pressure and heart failure. |
| Atenolol (Tenormin) | Selective beta-1 adrenergic blocker | Used for high blood pressure and angina. |
| Lisinopril (Prinivil, Zestril) | ACE inhibitor | Used for high blood pressure and heart failure. |
| Losartan (Cozaar) | Angiotensin II receptor blocker (ARB) | Used for high blood pressure and heart failure. |
Carvedilol Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | Worsening heart failure |
| Fatigue | Severe hypotension |
| Diarrhea | Bronchospasm |
| Weakness | Heart block |
| Hypotension | Slow Heartbeat |
Carvedilol Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hypertension | 6.25 mg twice daily | 6.25 mg to 25 mg twice daily | Take with food to minimize dizziness. |
| Heart Failure | 3.125 mg twice daily | Target maintenance dose as tolerated (up to 25 mg twice daily for patients 85kg) | Increase dose gradually under medical supervision. |
| Post-MI with Left Ventricular Dysfunction | 6.25 mg twice daily | Target maintenance dose as tolerated (up to 25 mg twice daily) | Titrate slowly as tolerated. |
Carvedilol Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10-$30 |
| Without Insurance (U.S.) | $20-$50 |
| From Canada | $32.40 |

