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General Medication Fact Sheet for Chlorthalidone
| Field | Information |
|---|---|
| Generic Name | Chlorthalidone |
| Brand Name Versions | Hygroton, Thalitone |
| Purpose | Treats high blood pressure (hypertension) and fluid retention (edema) |
| Mechanism of Action | Increases the amount of salt and water removed by the kidneys |
| Dosage Forms | Oral tablets |
| Available Strengths | 12.5 mg, 25 mg, 50 mg, 100 mg |
| Dosage Frequency | Usually once daily |
| Common Side Effects | Dizziness, lightheadedness, stomach upset, muscle cramps |
| Serious Side Effects | Electrolyte imbalance (low potassium, low sodium), dehydration, gout, increased blood sugar |
| Drug Interactions | Digoxin, lithium, other diuretics, NSAIDs, corticosteroids, antidiabetic medications |
| Important Notes | Monitor electrolyte levels regularly; may increase sensitivity to sunlight; consult a doctor if you experience muscle weakness or irregular heartbeat |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Hydrochlorothiazide, Losartan, Amlodipine, Lisinopril |
Chlorthalidone Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Hydrochlorothiazide (Microzide) | Thiazide diuretic; increases excretion of sodium and water | Similar to chlorthalidone, but may have a shorter duration of action. |
| Losartan (Cozaar) | Angiotensin II receptor blocker (ARB); relaxes blood vessels | An alternative for those who cannot tolerate diuretics. |
| Amlodipine (Norvasc) | Calcium channel blocker; relaxes and widens blood vessels | An alternative for those who cannot tolerate diuretics. |
| Lisinopril (Prinivil, Zestril) | ACE inhibitor; blocks the production of angiotensin II | An alternative for those who cannot tolerate diuretics. |
Chlorthalidone Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | Electrolyte imbalance (low potassium, low sodium) |
| Lightheadedness | Dehydration |
| Stomach upset | Gout |
| Muscle cramps | Increased blood sugar |
| Increased urination | Kidney problems |
Chlorthalidone Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hypertension | 12.5 mg to 25 mg daily | 12.5 mg to 50 mg daily | Take in the morning to avoid nighttime urination. |
| Edema | 50 mg daily | 50 mg to 100 mg daily or on alternate days | Adjust dose based on individual response. |
Chlorthalidone Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 |
| Without Insurance (U.S.) | $25 – $70 |
| From Canada | $18.50 |
