Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Comfortis Chewable Tablets
| Field | Information |
|---|---|
| Medication Name | Comfortis Chewable Tablets |
| Generic Name | Spinosad |
| Boxed/Label Warning | Not applicable |
| Purpose | Flea treatment for dogs and cats |
| Mechanism of Action | Spinosad disrupts the nervous system of fleas, causing paralysis and death. |
| Dosage Forms | Chewable Tablets |
| Available Strengths | 56 mg, 140 mg, 270 mg, 560 mg, 810 mg, 1620 mg |
| Dosage Frequency | Once a month |
| Common Side Effects | Vomiting, decreased appetite, lethargy or depression, increased thirst, diarrhea, incoordination, skin redness |
| Serious Side Effects | Seizures (rare), allergic reactions (hives, facial swelling, difficulty breathing) |
| Drug Interactions | Ivermectin (use with caution), other flea and tick preventatives (consult veterinarian) |
| Important Notes | Administer with food for optimal absorption. Use caution in animals with a history of seizures. Consult a veterinarian before use. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Administer as soon as you remember, then resume monthly dosing schedule. |
| Alternatives | Capstar (nitenpyram), Frontline (fipronil), Advantage (imidacloprid), NexGard (afoxolaner) |
Comfortis Chewable Tablets Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Capstar (nitenpyram) | Nervous system disruption | Rapidly kills adult fleas; short duration of action. |
| Frontline (fipronil) | Nervous system disruption | Topical application; kills adult fleas and ticks. |
| Advantage (imidacloprid) | Nervous system disruption | Topical application; kills adult fleas. |
| NexGard (afoxolaner) | Nervous system disruption | Oral chewable; kills adult fleas and ticks. |
Comfortis Chewable Tablets Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Vomiting (especially after the first dose) | Seizures or convulsions |
| Decreased appetite | Ataxia (loss of balance, stumbling, uncoordinated movement) |
| Lethargy or depression | Muscle tremors |
| Diarrhea | Severe or persistent vomiting that prevents keeping the tablet down |
Comfortis Chewable Tablets Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Flea Infestation (Dogs) | 13.5 mg/lb (30 mg/kg) | 13.5 mg/lb (30 mg/kg) monthly | Administer with food. Choose appropriate tablet strength based on weight. |
| Flea Infestation (Cats) | 13.5 mg/lb (30 mg/kg) | 13.5 mg/lb (30 mg/kg) monthly | Administer with food. Choose appropriate tablet strength based on weight. |
Comfortis Chewable Tablets Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 |
| Without Insurance (U.S.) | $90 |
| From Canada |
