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Diamicron MR (Gliclazide)
General Medication Fact Sheet for Diamicron MR
| Field | Information |
|---|---|
| Medication Name | Diamicron MR |
| Generic Name | Gliclazide |
| Boxed/Label Warning | None |
| Purpose | To lower blood sugar in adults with type 2 diabetes mellitus |
| Mechanism of Action | Stimulates insulin release from pancreatic beta cells and increases insulin sensitivity. |
| Dosage Forms | Modified-release tablets |
| Available Strengths | 30 mg, 60 mg |
| Dosage Frequency | Once daily, usually in the morning |
| Common Side Effects | Hypoglycemia (low blood sugar), nausea, diarrhea, abdominal pain |
| Serious Side Effects | Severe hypoglycemia, liver problems, allergic reactions |
| Drug Interactions | Other antidiabetic drugs, nonsteroidal anti-inflammatory drugs (NSAIDs), certain antifungal medications (e.g., fluconazole), alcohol, ACE inhibitors, beta-blockers, warfarin |
| Important Notes | Take as directed by your healthcare provider. Monitor blood sugar levels regularly. Be aware of symptoms of hypoglycemia. Avoid alcohol consumption. |
| Storage | Store at room temperature away from moisture and light. Keep out of reach of children. |
| Missed Dose | Take as soon as you remember, unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | Glipizide, Glimepiride, Metformin, Januvia (sitagliptin) |
Diamicron MR Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Glipizide (Glucotrol) | Sulfonylurea: Stimulates insulin release from the pancreas. | Similar mechanism to gliclazide. Short-acting. |
| Glimepiride (Amaryl) | Sulfonylurea: Stimulates insulin release from the pancreas. | Longer-acting than Glipizide, also a sulfonylurea. |
| Metformin (Glucophage) | Biguanide: Decreases glucose production in the liver and improves insulin sensitivity. | First-line treatment for type 2 diabetes, often used in combination. |
| Sitagliptin (Januvia) | DPP-4 inhibitor: Increases incretin levels, which stimulate insulin release and decrease glucagon secretion. | Different mechanism than sulfonylureas, often used in combination. |
Diamicron MR Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Hypoglycemia (low blood sugar) | Severe hypoglycemia (confusion, seizures, loss of consciousness) |
| Nausea | Liver problems (jaundice, abdominal pain) |
| Diarrhea | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Abdominal pain | Blood disorders (rare) |
Diamicron MR Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Type 2 Diabetes | 30 mg once daily | 30-120 mg once daily | Take orally in the morning, preferably at breakfast. Adjust dose gradually based on blood glucose levels. |
Diamicron MR Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | NA |
| Without Insurance (U.S.) | NA |
| From CPS | $ |
