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General Medication Fact Sheet for Diclectin
| Field | Information |
|---|---|
| Medication Name | Diclectin |
| Generic Name | Doxylamine succinate and pyridoxine hydrochloride |
| Purpose | Used to treat nausea and vomiting of pregnancy (NVP). |
| Mechanism of Action | Doxylamine is an antihistamine that blocks histamine receptors, and pyridoxine is a form of vitamin B6. The exact mechanism in NVP is unknown, but they likely act synergistically to reduce nausea and vomiting. |
| Dosage Forms | Delayed-release tablets |
| Available Strengths | 10 mg doxylamine succinate/10 mg pyridoxine hydrochloride |
| Dosage Frequency | Usually taken once daily at bedtime, increasing to twice daily or three times daily if needed. Consult your doctor. |
| Common Side Effects | Drowsiness, dry mouth, dizziness, constipation. |
| Serious Side Effects | Severe drowsiness, confusion, rapid heart rate, difficulty urinating (rare). |
| Drug Interactions | Other sedatives, antihistamines, alcohol, MAO inhibitors. Consult your doctor or pharmacist. |
| Important Notes | Take on an empty stomach with a glass of water. Do not crush, chew, or split the tablets. Avoid alcohol while taking this medication. If drowsiness is severe, contact your doctor. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | If you miss a dose, skip the missed dose and take the next dose at the regular time. Do not double the dose. |
| Alternatives | Ginger, Vitamin B6 (pyridoxine), Promethazine, Ondansetron. Consult your doctor. |
Diclectin Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Ginger | Unknown, but may affect gastrointestinal motility and inflammation | Available in various forms, including capsules, candies, and teas. Often used as a natural remedy. |
| Vitamin B6 (Pyridoxine) | Coenzyme involved in numerous metabolic functions | May be effective for mild nausea. Often used in combination with doxylamine (as in Diclegis/Diclectin). |
| Promethazine (Phenergan) | Antihistamine and antiemetic | Prescription medication; can cause significant drowsiness. |
| Ondansetron (Zofran) | Serotonin 5-HT3 receptor antagonist | Prescription medication; typically reserved for severe nausea and vomiting. |
Diclectin Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Drowsiness | Severe drowsiness |
| Dry Mouth | Confusion |
| Dizziness | Rapid heart rate |
| Constipation | Difficulty urinating (rare) |
| Headache | Allergic reaction (rash, itching, swelling) |
Diclectin Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Nausea and Vomiting of Pregnancy (NVP) | 1 tablet at bedtime | 1 tablet at bedtime; may increase to 1 tablet in the morning and 1 tablet at bedtime, and then 1 tablet in the morning, 1 tablet midday, and 1 tablet at bedtime if needed. | Take on an empty stomach with a glass of water. Do not exceed 3 tablets in 24 hours. Consult your doctor. |
Diclectin Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 – $60 |
| Without Insurance (U.S.) | $680 – $750 |
| From CPS | $206.95 |
