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General Medication Fact Sheet for Doxazosin
| Field | Information |
|---|---|
| Generic Name | Doxazosin |
| Brand Name Versions | Cardura |
| Boxed/Label Warning | None |
| Purpose | Treats hypertension (high blood pressure) and benign prostatic hyperplasia (BPH) |
| Mechanism of Action | Alpha-1 adrenergic receptor blocker, relaxing blood vessels and prostate muscles |
| Dosage Forms | Oral tablets |
| Available Strengths | 1 mg, 2 mg, 4 mg, 8 mg |
| Dosage Frequency | Once daily, typically at bedtime |
| Common Side Effects | Dizziness, fatigue, headache, orthostatic hypotension (low blood pressure upon standing) |
| Serious Side Effects | Fainting, prolonged erection (priapism), severe hypotension |
| Drug Interactions | Other blood pressure medications, PDE5 inhibitors (e.g., sildenafil, tadalafil) |
| Important Notes | May cause dizziness, especially when starting treatment or increasing the dose; change positions slowly to avoid falls. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Terazosin, Alfuzosin, Tamsulosin, Prazosin |
Doxazosin Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Terazosin | Alpha-1 adrenergic receptor blocker | Similar to doxazosin, used for hypertension and BPH. |
| Alfuzosin (Uroxatral) | Selective alpha-1 adrenergic receptor blocker | Primarily used for BPH; may have fewer blood pressure-lowering effects. |
| Tamsulosin (Flomax) | Selective alpha-1A adrenergic receptor blocker | Primarily used for BPH; targets prostate alpha-1A receptors. |
| Prazosin | Alpha-1 adrenergic receptor blocker | Used for hypertension, PTSD, and Raynaud’s phenomenon. |
Doxazosin Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | Fainting |
| Fatigue | Prolonged erection (priapism) |
| Headache | Severe hypotension |
| Orthostatic hypotension (low blood pressure upon standing) | Fluid retention (edema) |
| Nasal congestion | Irregular heartbeat |
Doxazosin Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hypertension | 1 mg daily | 1-16 mg daily (adjust based on blood pressure) | Take at bedtime to minimize dizziness. |
| Benign Prostatic Hyperplasia (BPH) | 1 mg daily | 1-8 mg daily (adjust based on symptom relief) | Take at bedtime to minimize dizziness. |
Doxazosin Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $15 |
| Without Insurance (U.S.) | $15 – $40 |
| From Canada | $12 |
