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General Medication Fact Sheet for Durolane Syringe
| Field | Information |
|---|---|
| Medication Name | Durolane Syringe |
| Generic Name | Hyaluronic Acid |
| Purpose | Viscosupplementation for osteoarthritis knee pain relief. |
| Mechanism of Action | Replaces and supplements the natural hyaluronic acid in the joint, providing lubrication and cushioning. |
| Dosage Forms | Single-injection syringe |
| Available Strengths | 20 mg/mL |
| Dosage Frequency | Single intra-articular injection |
| Common Side Effects | Injection site pain, swelling, stiffness, warmth, redness, bruising. |
| Serious Side Effects | Severe allergic reaction (rash, itching, swelling, dizziness, trouble breathing), signs of infection (increased pain, swelling, redness, fever). |
| Drug Interactions | Avoid using disinfectants containing quaternary ammonium salts for skin preparation before injection. |
| Important Notes | Not for intravenous use. Not for use in patients with known hypersensitivity to hyaluronic acid preparations. Report any allergic reactions or signs of infection to your doctor immediately. |
| Storage | Store at room temperature, protect from freezing. |
| Missed Dose | Since it is a single injection, a missed dose is not applicable. |
| Alternatives | Synvisc, Hyalgan, Orthovisc, Corticosteroid injections, Physical Therapy |
Durolane Syringe Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Synvisc (Hyaluronic Acid) | Viscosupplementation | Requires multiple injections. |
| Hyalgan (Hyaluronic Acid) | Viscosupplementation | Requires multiple injections. |
| Orthovisc (Hyaluronic Acid) | Viscosupplementation | Requires multiple injections. |
| Corticosteroid Injections | Reduces inflammation | Provides short-term pain relief. |
Durolane Syringe Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Injection site pain | Signs of a severe allergic reaction (rash, hives, itching, swelling of face/throat, difficulty breathing) |
| Swelling | Signs of a joint infection (fever, chills, severe and persistent pain, warmth, and redness of the knee) |
| Stiffness | Severe and persistent joint swelling |
| Warmth | |
| Redness | |
| Bruising |
Durolane Syringe Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Osteoarthritis Knee Pain | 60 mg (single injection) | Not applicable (single injection) | Administered intra-articularly by a healthcare professional. |
Durolane Syringe Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $100 |
| Without Insurance (U.S.) | $400 – $50 |
| From CPS | $424.95 |
