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General Medication Fact Sheet for Dutasteride
| Field | Information |
|---|---|
| Generic Name | Dutasteride |
| Brand Name Versions | Avodart |
| Purpose | Treatment of benign prostatic hyperplasia (BPH) |
| Mechanism of Action | 5-alpha reductase inhibitor, blocking the conversion of testosterone to dihydrotestosterone (DHT) |
| Dosage Forms | Oral capsules |
| Available Strengths | 0.5 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Impotence, decreased libido, ejaculation problems, enlarged breasts |
| Serious Side Effects | Allergic reactions (rash, itching, swelling), depression |
| Drug Interactions | Certain antifungals (e.g., ketoconazole), cimetidine |
| Important Notes | Women who are pregnant or may become pregnant should not handle dutasteride capsules due to the potential risk to a male fetus. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Finasteride, Tamsulosin, Alfuzosin, Terazosin, Doxazosin |
Dutasteride Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Finasteride (Proscar, Propecia) | 5-alpha reductase inhibitor (Type II) | Similar to dutasteride but primarily inhibits type II 5-alpha reductase. Also used for male pattern baldness. |
| Tamsulosin (Flomax) | Alpha-1 adrenergic blocker | Relaxes muscles in the prostate and bladder neck, improving urine flow. |
| Alfuzosin (Uroxatral) | Alpha-1 adrenergic blocker | Similar to Tamsulosin in mechanism and use. |
| Terazosin (Hytrin) | Alpha-1 adrenergic blocker | Also used to treat hypertension. |
| Doxazosin (Cardura) | Alpha-1 adrenergic blocker | Also used to treat hypertension. |
Dutasteride Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Impotence | Allergic reactions (rash, itching, swelling) |
| Decreased libido | Depression |
| Ejaculation problems | Testicular pain or swelling |
Dutasteride Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Benign Prostatic Hyperplasia (BPH) | 0.5 mg | 0.5 mg once daily | Swallow capsules whole; do not chew or open. Can be taken with or without food. |
Dutasteride Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 |
| Without Insurance (U.S.) | $10 – $25 |
| From CPS | $12.10 |
