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General Medication Fact Sheet for Edex
| Field | Information |
|---|---|
| Medication Name | Edex |
| Generic Name | Alprostadil |
| Purpose | Treatment of erectile dysfunction (ED) |
| Mechanism of Action | Relaxes smooth muscle in the penis, allowing blood to flow into the penis, causing an erection |
| Dosage Forms | Injectable solution |
| Available Strengths | 10 mcg, 20 mcg, 40 mcg |
| Dosage Frequency | As needed, no more than once per day and no more than three times per week, with at least 24 hours between each dose. |
| Common Side Effects | Penile pain, localized pain at the injection site, minor bleeding or bruising at the injection site, dizziness |
| Serious Side Effects | Prolonged erection (priapism) lasting longer than 4 hours, fibrosis of the penis, painful erection, hypotension |
| Drug Interactions | Antihypertensives (may increase risk of hypotension), anticoagulants (may increase risk of bleeding at injection site) |
| Important Notes | Use exactly as prescribed by your doctor. Proper injection technique is crucial. Seek immediate medical attention if you experience an erection lasting longer than 4 hours. |
| Storage | Store in the refrigerator (36°F to 46°F) until dispensed. Once dispensed, can be stored at room temperature (up to 77°F) for up to 3 months. |
| Missed Dose | Not applicable, as Edex is used on an as-needed basis. |
| Alternatives | Sildenafil (Viagra), Tadalafil (Cialis), Vardenafil (Levitra), Avanafil (Stendra), Bimix/Trimix |
Edex Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Sildenafil (Viagra) | PDE5 inhibitor; increases blood flow to the penis. | Oral medication, taken as needed before sexual activity. |
| Tadalafil (Cialis) | PDE5 inhibitor; increases blood flow to the penis. | Oral medication, can be taken daily or as needed. |
| Vardenafil (Levitra) | PDE5 inhibitor; increases blood flow to the penis. | Oral medication, taken as needed before sexual activity. |
| Avanafil (Stendra) | PDE5 inhibitor; increases blood flow to the penis. | Oral medication, faster onset than other PDE5 inhibitors. |
| Bimix/Trimix | Mixture of medications (often including alprostadil) that cause vasodilation. | Injected directly into the penis, similar to Edex. Requires compounding pharmacy. |
Edex Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Penile pain | Priapism (prolonged erection lasting longer than 4 hours) |
| Localized pain at the injection site | Fibrosis of the penis (scarring) |
| Minor bleeding or bruising at the injection site | Painful erection |
| Dizziness | Hypotension (low blood pressure) |
| Headache | Hematoma at injection site |
Edex Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Erectile Dysfunction | Varies based on individual response; typically 2.5 to 20 mcg | Varies based on individual response; adjust to lowest effective dose | Administer by intracavernosal injection. Titrate the dose under medical supervision. Use no more than once in 24 hours and no more than 3 times per week. Alternate injection sites. |
Edex Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $40 – $100 |
| Without Insurance (U.S.) | $90 – $750 |
| From CPS | $87.95 |
