Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Effient
| Field | Information |
|---|---|
| Medication Name | Effient |
| Generic Name | Prasugrel |
| Boxed/Label Warning | Significant, sometimes fatal, bleeding. Not recommended in patients ≥75 years old due to increased risk of fatal bleeding. Avoid use in patients with active bleeding or a history of stroke or TIA. |
| Purpose | To reduce the rate of thrombotic cardiovascular events (e.g., stent thrombosis) in patients with acute coronary syndrome (ACS) who are managed with percutaneous coronary intervention (PCI). |
| Mechanism of Action | Prasugrel is a thienopyridine class antiplatelet agent that inhibits platelet activation and aggregation through irreversible binding of its active metabolite to the P2Y12 ADP receptor on platelets. |
| Dosage Forms | Oral tablets |
| Available Strengths | 5 mg, 10 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Bleeding, bruising, nosebleeds, anemia |
| Serious Side Effects | Severe bleeding (including life-threatening bleeding), Thrombotic Thrombocytopenic Purpura (TTP), allergic reactions |
| Drug Interactions | Other antiplatelet drugs (e.g., aspirin, Clopidogrel), anticoagulants (e.g., warfarin, heparin), NSAIDs, certain antidepressants (SSRIs, SNRIs) |
| Important Notes | Inform your doctor if you have any upcoming surgeries or dental procedures. Monitor for signs of bleeding. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose. |
| Alternatives | Clopidogrel (Plavix), Ticagrelor (Brilinta), Aspirin |
Effient Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Clopidogrel (Plavix) | Inhibits platelet aggregation by selectively preventing the binding of adenosine diphosphate (ADP) to its platelet P2Y12 receptor. | A commonly prescribed antiplatelet medication; may be preferred in some patients due to cost or other factors. |
| Ticagrelor (Brilinta) | Reversibly interacts with the platelet P2Y12 ADP receptor to prevent signal transduction and platelet aggregation. | Another P2Y12 inhibitor; has a faster onset and offset of action compared to Clopidogrel. |
| Aspirin | Irreversibly inhibits cyclooxygenase-1 (COX-1) and reduces thromboxane A2 (TXA2) production, leading to decreased platelet aggregation. | Often used in combination with a P2Y12 inhibitor for dual antiplatelet therapy (DAPT). |
Effient Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Bleeding (e.g., nosebleeds, bruising) | Severe bleeding (including life-threatening bleeding) |
| Anemia | Thrombotic Thrombocytopenic Purpura (TTP) |
| Headache | Allergic reactions (rash, itching, swelling, difficulty breathing) |
Effient Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Acute Coronary Syndrome (ACS) with PCI | 60 mg loading dose | 10 mg once daily | Loading dose should be administered as soon as possible following diagnosis of ACS and before or immediately after PCI. |
| ACS with PCI (patients <60 kg) | 60 mg loading dose | 5 mg once daily | A lower maintenance dose may be considered in patients weighing less than 60 kg. |
Effient Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | NA |
| Without Insurance (U.S.) | $10 – $50 |
| From Canada | $ |
