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Eliquis (Apixaban)
| Apixaban (Generic) Apixaban | ||||||
Shipped from United Kingdom | ||||||
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| Apixaban (Generic) Apixaban | ||||||
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Shipped from Mauritius | ||||||
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| Auro-Apixaban (Generic) Apixaban | ||||||
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Shipped from Canada | ||||||
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| Jamp-Apixaban (Generic) Apixaban | ||||||
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Shipped from Canada | ||||||
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| Taro-Apixaban (Generic) Apixaban | ||||||
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Shipped from Canada | ||||||
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General Medication Fact Sheet for Eliquis
| Field | Information |
|---|---|
| Medication Name | Eliquis |
| Generic Name | Apixaban |
| Boxed/Label Warning | Risk of stroke with discontinuation; risk of spinal/epidural hematoma with neuraxial anesthesia |
| Purpose | Anticoagulant used to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation and for the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE). |
| Mechanism of Action | Directly inhibits factor Xa, a key component of the blood coagulation cascade. |
| Dosage Forms | Oral tablets |
| Available Strengths | 2.5 mg, 5 mg |
| Dosage Frequency | Typically twice daily |
| Common Side Effects | Bleeding (e.g., nosebleeds, bruising), nausea |
| Serious Side Effects | Major bleeding events (e.g., gastrointestinal bleeding, intracranial hemorrhage), allergic reactions |
| Drug Interactions | Strong CYP3A4 inhibitors (e.g., ketoconazole), strong CYP3A4 inducers (e.g., rifampin), other anticoagulants (e.g., Warfarin), antiplatelet agents (e.g., aspirin, clopidogrel) |
| Important Notes | Inform your doctor of all medications and supplements you are taking; discuss any planned surgeries or dental procedures; monitor for signs of bleeding. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take the missed dose as soon as you remember on the same day. Do not take two doses at the same time to make up for a missed dose. |
| Alternatives | Warfarin (Coumadin, Jantoven), Rivaroxaban (Xarelto), Dabigatran (Pradaxa), Edoxaban (Savaysa) |
Eliquis Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Warfarin (Coumadin, Jantoven) | Vitamin K antagonist | Requires regular blood monitoring (INR). |
| Rivaroxaban (Xarelto) | Direct factor Xa inhibitor | Once-daily dosing available. |
| Dabigatran (Pradaxa) | Direct thrombin inhibitor | Available with a reversal agent (idarucizumab). |
| Edoxaban (Savaysa) | Direct factor Xa inhibitor | Once-daily dosing available, specific criteria for use in atrial fibrillation. |
Eliquis Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Bleeding (nosebleeds, bruising) | Major bleeding events (gastrointestinal, intracranial) |
| Nausea | Allergic reactions (rash, itching, swelling) |
| Anemia | Spinal or epidural hematoma (rare) |
Eliquis Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Nonvalvular Atrial Fibrillation | 5 mg twice daily | 5 mg twice daily (may be reduced to 2.5 mg twice daily based on age, weight, and kidney function) | Take with or without food. |
| DVT/PE Treatment | 10 mg twice daily for 7 days | 5 mg twice daily | Take with or without food. |
| DVT/PE Prevention | 2.5 mg twice daily after initial treatment | 2.5 mg twice daily | Take with or without food. |
