Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Enhertu
| Field | Information |
|---|---|
| Medication Name | Enhertu |
| Generic Name | Trastuzumab deruxtecan |
| Boxed/Label Warning | Interstitial Lung Disease (ILD) and Embryo-Fetal Toxicity |
| Purpose | HER2-directed antibody and topoisomerase inhibitor conjugate indicated for certain HER2-positive cancers. |
| Mechanism of Action | Binds to HER2-expressing cancer cells, is internalized, and releases a topoisomerase I inhibitor (DXd), causing DNA damage and cell death. |
| Dosage Forms | Lyophilized powder for intravenous infusion |
| Available Strengths | 100 mg |
| Dosage Frequency | Every 3 weeks (21-day cycle) |
| Common Side Effects | Nausea, fatigue, vomiting, alopecia, constipation, decreased appetite, anemia, neutropenia, thrombocytopenia |
| Serious Side Effects | Interstitial Lung Disease (ILD), pneumonitis, cardiac dysfunction (decreased left ventricular ejection fraction), embryo-fetal toxicity, infusion-related reactions, neutropenia |
| Drug Interactions | No formal drug interaction studies have been conducted. |
| Important Notes | Monitor for signs and symptoms of ILD/pneumonitis; assess cardiac function prior to and during treatment; use effective contraception during treatment and for at least 7 months after the last dose. |
| Storage | Store vials in a refrigerator at 2°C to 8°C (36°F to 46°F) until time of use. |
| Missed Dose | Contact your doctor immediately to reschedule your appointment. Do not attempt to administer a missed dose on your own. |
| Alternatives | T-DM1 (Kadcyla), Fam-trastuzumab deruxtecan-nxki (Enhertu), Trastuzumab (Herceptin) in combination with other chemotherapy agents, Lapatinib (Tykerb) in combination with capecitabine. |
Enhertu Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| T-DM1 (Kadcyla) | HER2-targeted antibody-drug conjugate that delivers a cytotoxic agent (DM1) to HER2-positive cells. | Indicated for HER2-positive, metastatic breast cancer in patients who have received prior treatment with trastuzumab and a taxane. |
| Trastuzumab (Herceptin) + Chemotherapy | HER2-targeted antibody that inhibits HER2 signaling and recruits immune cells to kill HER2-positive cancer cells. | Often used in combination with chemotherapy for HER2-positive breast cancer. |
| Lapatinib (Tykerb) + Capecitabine | Tyrosine kinase inhibitor that targets HER2 and EGFR. Capecitabine is a chemotherapy agent. | Used in combination for HER2-positive, metastatic breast cancer in patients who have progressed on prior trastuzumab therapy. |
Enhertu Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Interstitial Lung Disease (ILD)/Pneumonitis |
| Fatigue | Cardiac Dysfunction (Decreased LVEF) |
| Vomiting | Neutropenia (Low White Blood Cell Count) |
| Alopecia (Hair Loss) | Thrombocytopenia (Low Platelet Count) |
| Constipation | Infusion-Related Reactions |
| Decreased Appetite | Embryo-Fetal Toxicity |
Enhertu Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| HER2-positive Breast Cancer (Metastatic) | 5.4 mg/kg | 5.4 mg/kg every 3 weeks | Administered as an intravenous infusion. Premedication may be required to reduce infusion-related reactions. |
| HER2-positive Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (Metastatic) | 6.4 mg/kg | 6.4 mg/kg every 3 weeks | Administered as an intravenous infusion. Premedication may be required to reduce infusion-related reactions. |
Enhertu Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $100 – $500 |
| Without Insurance (U.S.) | $13,000 – $15,000 |
| From CPS | $3,843 |
Why Americans Buy Enhertu from Canada Pharmacy Store?
Why Americans Buy Enhertu from Canada Pharmacy Store?
Americans have trouble affording Enhertu due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Enhertu prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Enhertu prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Enhertu Online
How to Order Enhertu Online
Step 1
Select Your Prescribed Enhertu Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Enhertu Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Enhertu Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Enhertu you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Enhertu at a lower price, simply place your order above or give us a call at 1-888-903-2240
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