Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Entresto
| Field | Information |
|---|---|
| Medication Name | Entresto |
| Generic Name | Sacubitril/Valsartan |
| Boxed/Label Warning | Pregnancy: Can cause injury or death to the unborn baby. Avoid use in pregnancy. |
| Purpose | Used to reduce the risk of cardiovascular death and hospitalization for heart failure in adults. |
| Mechanism of Action | Sacubitril enhances natriuretic peptides, while valsartan blocks the effects of angiotensin II, leading to vasodilation and reduced sodium retention. |
| Dosage Forms | Oral tablets |
| Available Strengths | 24/26 mg, 49/51 mg, 97/103 mg (sacubitril/valsartan) |
| Dosage Frequency | Typically twice daily, as directed by your healthcare provider. |
| Common Side Effects | Hypotension (low blood pressure), hyperkalemia (high potassium), dizziness, cough, kidney problems. |
| Serious Side Effects | Angioedema (swelling of the face, lips, tongue, or throat), severe allergic reactions, kidney failure. |
| Drug Interactions | ACE inhibitors (e.g., lisinopril), aliskiren, NSAIDs (e.g., ibuprofen), potassium-sparing diuretics (e.g., spironolactone), lithium. |
| Important Notes | Do not take with ACE inhibitors. Monitor blood pressure, potassium levels, and kidney function. Inform your doctor if you are pregnant or breastfeeding. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take the missed dose as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. |
| Alternatives | Enalapril, Lisinopril, Furosemide, Spironolactone |
Entresto Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Enalapril (Vasotec) | ACE inhibitor | Reduces blood pressure and improves heart failure symptoms. |
| Lisinopril (Prinivil, Zestril) | ACE inhibitor | Another common ACE inhibitor used for heart failure and hypertension. |
| Furosemide (Lasix) | Loop diuretic | Reduces fluid retention and relieves symptoms of heart failure. |
| Spironolactone (Aldactone) | Aldosterone antagonist (potassium-sparing diuretic) | Reduces fluid retention and protects the heart in heart failure. |
Entresto Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Hypotension (low blood pressure) | Angioedema (swelling of the face, lips, tongue, or throat) |
| Hyperkalemia (high potassium levels) | Kidney failure |
| Dizziness | Severe allergic reactions (rash, itching, hives, difficulty breathing) |
Entresto Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Heart Failure (NYHA Class II-IV) | 49/51 mg twice daily (if not already on ACE inhibitor or ARB, or on low doses) | Target dose: 97/103 mg twice daily, as tolerated | Swallow whole with water. May be taken with or without food. |
| Heart Failure (Switching from ACE Inhibitor) | 36 hours after the last dose of the ACE inhibitor, start Entresto at 49/51 mg twice daily. | Target dose: 97/103 mg twice daily, as tolerated | Swallow whole with water. May be taken with or without food. |
Why Americans Buy Entresto from Canada Pharmacy Store?
Why Americans Buy Entresto from Canada Pharmacy Store?
Americans have trouble affording Entresto due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Entresto prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Entresto prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Entresto Online
How to Order Entresto Online
Step 1
Select Your Prescribed Entresto Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Entresto Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Entresto Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Entresto you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Entresto at a lower price, simply place your order above or give us a call at 1-888-903-2240
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