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General Medication Fact Sheet for Eucreas
| Field | Information |
|---|---|
| Medication Name | Eucreas |
| Generic Name | Metformin/Vildagliptin |
| Boxed/Label Warning | Lactic acidosis is a rare, but serious, metabolic complication that can occur due to Metformin accumulation. Assess renal function before initiating and regularly thereafter. |
| Purpose | Used to treat type 2 diabetes mellitus by controlling blood sugar levels. |
| Mechanism of Action | Metformin decreases glucose production in the liver and improves insulin sensitivity. Vildagliptin enhances incretin levels, increasing insulin release and decreasing glucagon levels. |
| Dosage Forms | Oral tablets |
| Available Strengths | 50mg/500mg, 50mg/850mg, 50mg/1000mg (Vildagliptin/Metformin) |
| Dosage Frequency | Typically twice daily, taken with meals |
| Common Side Effects | Nausea, vomiting, diarrhea, headache, flatulence |
| Serious Side Effects | Lactic acidosis, liver problems, pancreatitis, hypoglycemia |
| Drug Interactions | Insulin and other antidiabetic drugs, certain blood pressure medications (ACE inhibitors, ARBs), diuretics, corticosteroids, NSAIDs, alcohol |
| Important Notes | Take with food to reduce stomach upset. Monitor blood glucose levels regularly. Avoid excessive alcohol consumption. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember unless it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Janumet (sitagliptin/Metformin), Kombiglyze XR (saxagliptin/Metformin), Metformin, Vildagliptin (Galvus) |
Eucreas Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Janumet (sitagliptin/Metformin) | DPP-4 inhibitor/Biguanide | Combination of a DPP-4 inhibitor and Metformin. |
| Kombiglyze XR (saxagliptin/Metformin) | DPP-4 inhibitor/Biguanide | Extended-release combination of a DPP-4 inhibitor and Metformin. |
| Metformin | Biguanide | Decreases glucose production in the liver and improves insulin sensitivity. |
| Vildagliptin (Galvus) | DPP-4 inhibitor | Enhances incretin levels, increasing insulin release and decreasing glucagon levels. |
Eucreas Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Lactic acidosis |
| Vomiting | Liver problems |
| Diarrhea | Pancreatitis |
| Headache | Hypoglycemia (low blood sugar) |
| Flatulence | Allergic reactions (rash, itching, swelling) |
Eucreas Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Type 2 Diabetes | 50mg/500mg twice daily | Adjusted based on glycemic control, up to a maximum of 100mg vildagliptin daily and 2000mg Metformin daily. | Take with meals to reduce gastrointestinal side effects. |
Eucreas Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $ |
| Without Insurance (U.S.) | $ |
| From CPS | $ |
