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General Medication Fact Sheet for Exforge
| Field | Information |
|---|---|
| Medication Name | Exforge |
| Generic Name | Amlodipine Besylate/Valsartan |
| Boxed/Label Warning | Pregnancy Category D: Use in pregnancy can cause injury and even death to the developing fetus. |
| Purpose | Treatment of hypertension (high blood pressure). |
| Mechanism of Action | Amlodipine is a calcium channel blocker that dilates blood vessels; Valsartan is an angiotensin II receptor blocker (ARB) that prevents blood vessels from narrowing. |
| Dosage Forms | Oral tablets |
| Available Strengths | 5/160 mg, 5/320 mg, 10/160 mg, 10/320 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Dizziness, edema (swelling), headache |
| Serious Side Effects | Kidney problems, hyperkalemia (high potassium), severe allergic reaction, symptomatic hypotension. |
| Drug Interactions | Other blood pressure medications, potassium supplements, NSAIDs, ACE inhibitors, aliskiren, lithium, CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin). |
| Important Notes | Do not use if pregnant or planning to become pregnant. Monitor blood pressure regularly. Inform your doctor about any history of kidney or liver disease. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Amlodipine (Norvasc), Valsartan (Diovan), Losartan (Cozaar), Hydrochlorothiazide |
Exforge Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Amlodipine (Norvasc) | Calcium channel blocker | Reduces blood pressure by relaxing blood vessels. |
| Valsartan (Diovan) | Angiotensin II Receptor Blocker (ARB) | Prevents blood vessels from narrowing. |
| Losartan (Cozaar) | Angiotensin II Receptor Blocker (ARB) | An alternative ARB for hypertension. |
| Hydrochlorothiazide | Thiazide diuretic | Reduces blood volume, lowering blood pressure. Often combined with other antihypertensives. |
Exforge Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | Kidney problems |
| Edema (swelling) | Hyperkalemia (high potassium) |
| Headache | Severe allergic reaction (rash, itching, swelling, difficulty breathing) |
| Fatigue | Symptomatic hypotension (low blood pressure) |
| Nausea | Increased creatinine levels |
Exforge Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hypertension | 5/160 mg once daily | 5/160 mg to 10/320 mg once daily | Take at the same time each day. Dosage is individualized based on response. |
Exforge Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 – $50 |
| Without Insurance (U.S.) | $200 – $300 |
| From CPS | $28.95 |
