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General Medication Fact Sheet for Feldene
| Field | Information |
|---|---|
| Medication Name | Feldene |
| Generic Name | Piroxicam |
| Boxed/Label Warning | NSAIDs may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. NSAIDs also increase the risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. |
| Purpose | Non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. |
| Mechanism of Action | Inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis, thereby reducing inflammation and pain. |
| Dosage Forms | Oral capsules |
| Available Strengths | 10 mg, 20 mg |
| Dosage Frequency | Typically once daily, or as directed by a healthcare provider. |
| Common Side Effects | Heartburn, nausea, abdominal pain, diarrhea, constipation, headache, dizziness. |
| Serious Side Effects | Gastrointestinal bleeding, ulceration, perforation, kidney problems, liver problems, heart attack, stroke, high blood pressure, allergic reactions. |
| Drug Interactions | Other NSAIDs, anticoagulants (e.g., warfarin), aspirin, certain antidepressants (SSRIs), ACE inhibitors, diuretics, lithium. |
| Important Notes | Take with food to minimize stomach upset. Use the lowest effective dose for the shortest duration. Consult a doctor if you have heart, liver, or kidney problems. May increase sensitivity to the sun. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Ibuprofen, Naproxen, Celecoxib, Meloxicam |
Feldene Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Ibuprofen (Advil, Motrin) | Non-selective COX inhibitor | Commonly used for mild to moderate pain relief. |
| Naproxen (Aleve) | Non-selective COX inhibitor | Longer-lasting pain relief compared to ibuprofen. |
| Celecoxib (Celebrex) | Selective COX-2 inhibitor | May have a lower risk of gastrointestinal side effects compared to non-selective NSAIDs. |
| Meloxicam (Mobic) | Preferentially inhibits COX-2 over COX-1 | Once-daily NSAID. |
Feldene Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Heartburn | Gastrointestinal bleeding |
| Nausea | Kidney problems |
| Abdominal pain | Liver problems |
| Diarrhea | Heart attack |
| Constipation | Stroke |
| Headache | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
| Dizziness | High blood pressure |
Feldene Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Osteoarthritis | 20 mg | 20 mg once daily | Take with food. Use the lowest effective dose. |
| Rheumatoid Arthritis | 20 mg | 20 mg once daily | Take with food. Use the lowest effective dose. |
| Ankylosing Spondylitis | 20 mg | 20 mg once daily | Take with food. Use the lowest effective dose. |
Feldene Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $20 – $75 |
| Without Insurance (U.S.) | $400 – $500 |
| From CPS | $49.95 |
