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Florinef (Fludrocortisone)
| Fludrocortisone Acetate (Generic) Fludrocortisone Acetate | ||||||
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General Medication Fact Sheet for Florinef
| Field | Information |
|---|---|
| Medication Name | Florinef |
| Generic Name | Fludrocortisone |
| Purpose | Treats adrenocortical insufficiency (Addison’s disease) and salt-losing adrenogenital syndrome |
| Mechanism of Action | Acts as a mineralocorticoid, increasing sodium reabsorption and potassium excretion in the kidneys |
| Dosage Forms | Oral tablets |
| Available Strengths | 0.1 mg |
| Dosage Frequency | Usually once daily, but may vary |
| Common Side Effects | Headache, dizziness, swelling of ankles/feet, high blood pressure, weight gain |
| Serious Side Effects | Muscle weakness, severe headache, vision changes, mental/mood changes, signs of infection |
| Drug Interactions | Diuretics, digoxin, insulin or oral diabetes medications, NSAIDs, anticoagulants |
| Important Notes | Monitor blood pressure and electrolytes regularly; follow a low-salt diet as directed; report any signs of infection or unusual symptoms to your doctor |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; if it’s close to your next dose, skip the missed dose. Do not double the dose. |
| Alternatives | Hydrocortisone, Prednisone, Cortisone Acetate |
Florinef Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Hydrocortisone | Glucocorticoid and mineralocorticoid activity | Often used in combination with a mineralocorticoid. |
| Prednisone | Primarily glucocorticoid activity | May require additional mineralocorticoid supplementation. |
| Cortisone Acetate | Glucocorticoid and mineralocorticoid activity | Another option for adrenocortical insufficiency. |
Florinef Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Muscle weakness |
| Dizziness | Severe headache |
| Swelling of ankles/feet | Vision changes |
| High blood pressure | Mental/mood changes (e.g., depression, anxiety) |
| Weight gain | Signs of infection (e.g., fever, sore throat) |
Florinef Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Adrenocortical Insufficiency (Addison’s Disease) | 0.1 mg daily | 0.05 mg to 0.2 mg daily | Adjust dosage based on patient response and electrolyte levels. |
| Salt-Losing Adrenogenital Syndrome | 0.1 mg daily | Individualized based on clinical response | Monitor blood pressure and electrolytes regularly. |
Florinef Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 – $25 |
| Without Insurance (U.S.) | $80 – $120 |
| From CPS | $74.95 |
