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General Medication Fact Sheet for Fluphenazine
| Field | Information |
|---|---|
| Generic Name | Fluphenazine |
| Brand Name Versions | Prolixin |
| Boxed/Label Warning | Increased risk of death in elderly patients with dementia-related psychosis. |
| Purpose | Antipsychotic medication used to treat schizophrenia. |
| Mechanism of Action | Blocks dopamine receptors in the brain. |
| Dosage Forms | Oral tablets, oral solution, injection |
| Available Strengths | 1 mg, 2.5 mg, 5 mg, 10 mg |
| Dosage Frequency | Typically 2 to 4 times daily, or as directed by a healthcare provider. |
| Common Side Effects | Drowsiness, dizziness, blurred vision, dry mouth, constipation, muscle stiffness, tremors, restlessness |
| Serious Side Effects | Neuroleptic Malignant Syndrome (NMS), tardive dyskinesia, seizures, irregular heartbeat, severe allergic reaction, increased risk of stroke in elderly patients |
| Drug Interactions | Alcohol, other antipsychotics, antidepressants, anti-anxiety medications, anticholinergics, certain blood pressure medications |
| Important Notes | Avoid alcohol while taking this medication. May cause drowsiness; do not drive or operate heavy machinery until you know how this medication affects you. Consult your doctor before stopping this medication. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Haloperidol, Risperidone, Quetiapine, Aripiprazole |
Fluphenazine Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Haloperidol (Haldol) | Dopamine receptor antagonist | A typical antipsychotic, similar to fluphenazine. |
| Risperidone (Risperdal) | Dopamine and serotonin receptor antagonist | An atypical antipsychotic with a different side effect profile than fluphenazine. |
| Quetiapine (Seroquel) | Dopamine and serotonin receptor antagonist | An atypical antipsychotic often used for its sedative properties. |
| Aripiprazole (Abilify) | Dopamine and serotonin partial agonist | An atypical antipsychotic with a different mechanism of action compared to fluphenazine. |
Fluphenazine Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Drowsiness | Neuroleptic Malignant Syndrome (NMS) |
| Dizziness | Tardive dyskinesia |
| Blurred vision | Seizures |
| Dry mouth | Irregular heartbeat |
| Constipation | Severe allergic reaction (rash, itching, swelling, difficulty breathing) |
| Muscle stiffness | Increased risk of stroke in elderly patients |
Fluphenazine Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Schizophrenia | 2.5 to 10 mg daily | 1 to 40 mg daily (divided doses) | Adjust dosage based on individual response. |
| Psychotic Disorders | 2.5 to 10 mg daily | 1 to 40 mg daily (divided doses) | Administer orally or via injection (long-acting formulations available). |
Fluphenazine Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 – $30 |
| Without Insurance (U.S.) | $40 – $80 |
| From Canada | $15 – $35 |
