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General Medication Fact Sheet for Flurbiprofen
| Field | Information |
|---|---|
| Generic Name | Flurbiprofen |
| Brand Name Versions | Ocufen, Ansaid |
| Boxed/Label Warning | NSAIDs may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. NSAIDs may also increase the risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. |
| Purpose | Non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, fever, and inflammation. |
| Mechanism of Action | Inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis. |
| Dosage Forms | Oral tablets, ophthalmic solution |
| Available Strengths | 50 mg, 100 mg (oral); 0.03% (ophthalmic) |
| Dosage Frequency | Typically two to four times daily, or as directed by a healthcare provider (oral); as directed (ophthalmic) |
| Common Side Effects | Headache, dyspepsia, abdominal pain, nausea |
| Serious Side Effects | Gastrointestinal bleeding, kidney problems, heart problems, allergic reactions |
| Drug Interactions | Other NSAIDs, anticoagulants (e.g., warfarin), aspirin, certain antidepressants (SSRIs), ACE inhibitors, diuretics |
| Important Notes | Take with food to minimize stomach upset; consult a doctor if you have heart, liver, or kidney problems. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Ibuprofen, Naproxen, Diclofenac, Ketoprofen |
Flurbiprofen Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Ibuprofen (Advil, Motrin) | Non-selective COX inhibitor | Commonly used for mild to moderate pain relief. |
| Naproxen (Aleve) | Non-selective COX inhibitor | Longer-lasting pain relief compared to ibuprofen. |
| Diclofenac (Voltaren) | Non-selective COX inhibitor | Available in topical and oral forms. |
| Ketoprofen | Non-selective COX inhibitor | Similar to ibuprofen and Naproxen in its effects. |
Flurbiprofen Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Gastrointestinal bleeding |
| Dyspepsia | Kidney problems |
| Abdominal pain | Heart problems |
| Nausea | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Dizziness | Liver problems |
Flurbiprofen Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Rheumatoid Arthritis | 50 mg | 50-100 mg two to four times daily | Take with food. |
| Osteoarthritis | 50 mg | 50-100 mg two to four times daily | Take with food. |
| Pain Relief | 50 mg | 50-100 mg two to four times daily | Take with food. |
Flurbiprofen Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 |
| Without Insurance (U.S.) | $18 |
| From CPS | $ |
