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Fosrenol (Lanthanum)
| Lanthanum Carbonate (Generic) Lanthanum Carbonate | ||||||
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Shipped from Mauritius | ||||||
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General Medication Fact Sheet for Fosrenol
| Field | Information |
|---|---|
| Medication Name | Fosrenol |
| Generic Name | Lanthanum Carbonate |
| Purpose | Phosphate binder used to lower phosphate levels in patients with chronic kidney disease (CKD) on dialysis |
| Mechanism of Action | Binds to dietary phosphate in the gastrointestinal tract, forming insoluble lanthanum phosphate, which is excreted in the feces, thereby reducing phosphate absorption |
| Dosage Forms | Chewable tablets, Oral powder |
| Available Strengths | 500 mg, 750 mg, 1000 mg |
| Dosage Frequency | Typically taken with or immediately after meals |
| Common Side Effects | Nausea, vomiting, diarrhea, abdominal pain, constipation |
| Serious Side Effects | Bowel obstruction, severe constipation, fecal impaction, allergic reactions |
| Drug Interactions | Quinolone antibiotics (e.g., ciprofloxacin), levothyroxine, tetracycline antibiotics, calcium supplements, antacids |
| Important Notes | Must be taken with meals; chewable tablets should be chewed completely and not swallowed whole; consult a doctor if you experience severe gastrointestinal symptoms |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take with your next meal; do not double the dose |
| Alternatives | Sevelamer (Renvela, Renagel), Calcium Acetate, Aluminum Hydroxide |
Fosrenol Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Sevelamer (Renvela, Renagel) | Non-calcium, non-aluminum phosphate binder that binds phosphate in the GI tract | May be preferred in patients at risk of hypercalcemia. Available as Renvela (sevelamer carbonate) or Renagel (sevelamer hydrochloride). |
| Calcium Acetate (PhosLo) | Calcium-based phosphate binder that binds phosphate in the GI tract | Effective but may lead to hypercalcemia in some patients. |
| Aluminum Hydroxide | Aluminum-based phosphate binder that binds phosphate in the GI tract | Used less frequently due to potential aluminum toxicity with long-term use. |
Fosrenol Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Bowel obstruction |
| Vomiting | Severe constipation |
| Diarrhea | Fecal impaction |
| Abdominal pain | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Constipation | Perforation of the gastrointestinal tract |
Fosrenol Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hyperphosphatemia in CKD | 500 mg to 1000 mg | Adjusted based on phosphate levels; typically 750 mg to 3000 mg per day | Administer with or immediately after meals. Chewable tablets should be chewed completely and not swallowed whole. |
Fosrenol Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $50 |
| Without Insurance (U.S.) | $100 |
| From CPS | $ |
