Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Glyburide
| Field | Information |
|---|---|
| Generic Name | Glyburide |
| Brand Name Versions | DiaBeta, Glynase PresTab, Micronase |
| Boxed/Label Warning | Increased risk of cardiovascular death compared to diet alone or diet plus insulin. |
| Purpose | Used to treat type 2 diabetes mellitus by helping the pancreas produce insulin. |
| Mechanism of Action | Stimulates insulin release from the pancreatic beta cells and reduces glucose output from the liver. |
| Dosage Forms | Oral tablets |
| Available Strengths | 1.25 mg, 2.5 mg, 5 mg |
| Dosage Frequency | Usually once or twice daily, typically before meals, as directed by a healthcare provider. |
| Common Side Effects | Hypoglycemia (low blood sugar), nausea, heartburn. |
| Serious Side Effects | Severe hypoglycemia, allergic reactions, liver problems. |
| Drug Interactions | Insulin, other oral antidiabetic drugs, beta-blockers, NSAIDs, certain antibiotics, alcohol. |
| Important Notes | Monitor blood glucose levels regularly; follow dietary and exercise recommendations. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember unless it’s almost time for your next dose. Skip the missed dose and continue with your regular schedule. Do not double the dose. |
| Alternatives | Metformin, Glipizide, Glimepiride, Sitagliptin |
Glyburide Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Metformin (Glucophage) | Decreases hepatic glucose production and increases insulin sensitivity. | First-line treatment for type 2 diabetes. |
| Glipizide (Glucotrol) | Stimulates insulin release from the pancreatic beta cells. | Another sulfonylurea, similar to glyburide. |
| Glimepiride (Amaryl) | Stimulates insulin release from the pancreatic beta cells. | Longer-acting sulfonylurea. |
| Sitagliptin (Januvia) | Inhibits DPP-4, increasing incretin levels and insulin release. | DPP-4 inhibitor. |
Glyburide Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Hypoglycemia (low blood sugar) | Severe hypoglycemia (confusion, seizures, loss of consciousness) |
| Nausea | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Heartburn | Liver problems (jaundice, abdominal pain, dark urine) |
| Weight gain | Blood disorders (low blood counts) |
Glyburide Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Type 2 Diabetes | 2.5 mg | 1.25 mg to 20 mg daily | Take with breakfast or the first main meal. Adjust dose gradually based on blood glucose levels. |
Glyburide Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 |
| Without Insurance (U.S.) | $15 |
| From CPS | $8 |
