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General Medication Fact Sheet for Gonal F Pen
| Field | Information |
|---|---|
| Medication Name | Gonal F Pen |
| Generic Name | Follitropin alfa |
| Purpose | Stimulates follicle development in women undergoing fertility treatment; stimulates sperm production in men. |
| Mechanism of Action | Recombinant follicle-stimulating hormone (FSH) that binds to FSH receptors in the ovary or testes to stimulate gamete production. |
| Dosage Forms | Injectable solution in a prefilled pen |
| Available Strengths | 300 IU, 450 IU, 900 IU |
| Dosage Frequency | Typically administered once daily, as directed by a healthcare provider. |
| Common Side Effects | Headache, abdominal pain, nausea, ovarian hyperstimulation syndrome (OHSS; mild), injection site reactions |
| Serious Side Effects | Ovarian hyperstimulation syndrome (OHSS; severe), blood clots, ectopic pregnancy, multiple pregnancies |
| Drug Interactions | Clomiphene citrate, other fertility medications |
| Important Notes | Administer subcutaneously as directed by your doctor; monitor for signs of OHSS; follow instructions for pen use and storage. |
| Storage | Refrigerate unopened pens; once opened, store in the refrigerator for up to 28 days. Protect from light. |
| Missed Dose | Contact your doctor immediately for instructions. Do not administer a double dose. |
| Alternatives | Menopur (menotropin), Clomid (clomiphene citrate), Bravelle (follitropin alfa) |
Gonal F Pen Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Menopur (menotropin) | Contains both FSH and LH, stimulating follicle development. | Derived from human menopausal gonadotropin (hMG). |
| Clomid (clomiphene citrate) | Selective estrogen receptor modulator (SERM) that increases FSH and LH secretion. | Oral medication, often used as a first-line treatment for infertility. |
| Bravelle (follitropin alfa) | Recombinant FSH, similar to Gonal-F, stimulates follicle development. | Another brand of follitropin alfa. |
Gonal F Pen Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Ovarian hyperstimulation syndrome (OHSS; severe) |
| Abdominal pain | Blood clots (thromboembolism) |
| Nausea | Ectopic pregnancy |
| Ovarian hyperstimulation syndrome (OHSS; mild) | Multiple pregnancies (twins, triplets, etc.) |
| Injection site reactions (pain, redness, swelling) | Ovarian torsion |
Gonal F Pen Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Ovulation Induction | Varies based on individual response. | Adjusted based on ovarian response monitoring. | Administer subcutaneously; rotate injection sites. |
| Assisted Reproductive Technology (ART) | Varies based on individual response. | Adjusted based on ovarian response monitoring. | Administer subcutaneously; typically started on cycle day 2 or 3. |
| Male Infertility | Varies based on individual response. | Varies based on individual response. | Administer subcutaneously in conjunction with hCG. |
Gonal F Pen Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $50 |
| Without Insurance (U.S.) | $900 |
| From CPS | $492.20 |
