Harvoni (Ledipasvir,Sofosbuvir)

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Description

General Medication Fact Sheet for Harvoni

Field Information
Medication Name Harvoni
Generic Name Ledipasvir/Sofosbuvir
Boxed/Label Warning Reactivation of Hepatitis B Virus (HBV) has been reported in patients co-infected with Hepatitis C Virus (HCV) and HBV, some of which have resulted in serious liver problems or death. HCV/HBV co-infected patients should be tested for HBV infection before starting Harvoni.
Purpose Treatment of chronic Hepatitis C virus (HCV) infection in adults and children.
Mechanism of Action Ledipasvir inhibits the HCV NS5A protein, and sofosbuvir is a nucleotide analog inhibitor of the HCV NS5B polymerase.
Dosage Forms Oral tablets
Available Strengths 90 mg ledipasvir / 400 mg sofosbuvir
Dosage Frequency Once daily
Common Side Effects Fatigue, headache, weakness
Serious Side Effects Reactivation of Hepatitis B virus (HBV), slowed heart rate (bradycardia when used with amiodarone).
Drug Interactions Amiodarone, rifampin, St. John’s Wort, carbamazepine, phenytoin, oxcarbazepine, tipranavir/ritonavir, elbasvir/grazoprevir, tenofovir disoproxil fumarate.
Important Notes Harvoni is a complete treatment regimen for HCV. Do not take with other products containing sofosbuvir. Before starting Harvoni, tell your doctor about all of your medical conditions, including liver problems other than hepatitis C, kidney problems, and any other medical conditions.
Storage Store at room temperature away from moisture and light.
Missed Dose Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at one time.
Alternatives Epclusa (sofosbuvir/velpatasvir), Mavyret (glecaprevir/pibrentasvir), Vosevi (sofosbuvir/velpatasvir/voxilaprevir)

Harvoni Alternatives

Medication Mechanism of Action Notes
Epclusa (sofosbuvir/velpatasvir) Inhibits HCV NS5A and NS5B proteins. A single-tablet regimen for all 6 genotypes of HCV.
Mavyret (glecaprevir/pibrentasvir) Inhibits HCV NS3/4A protease and NS5A. A pan-genotypic treatment with a shorter treatment duration in some cases.
Vosevi (sofosbuvir/velpatasvir/voxilaprevir) Inhibits HCV NS5A and NS5B proteins, and NS3/4A protease. Used for patients who have failed previous treatment with other HCV medications.

Harvoni Side Effects

Common Side Effects Serious Side Effects
Fatigue Reactivation of Hepatitis B virus (HBV)
Headache Slowed heart rate (bradycardia, especially when taken with amiodarone)
Weakness Serious allergic reactions (rare)

Harvoni Dosage Guide

Condition Starting Dose Maintenance Dose Administration Notes
Chronic Hepatitis C (HCV) Genotype 1, 4, 5, or 6 90 mg ledipasvir/400 mg sofosbuvir 90 mg ledipasvir/400 mg sofosbuvir once daily Treatment duration varies based on prior treatment history and presence of cirrhosis.
HCV/HIV-1 Coinfection 90 mg ledipasvir/400 mg sofosbuvir 90 mg ledipasvir/400 mg sofosbuvir once daily Follow the same duration as for HCV monoinfection.

Harvoni Price With And Without Insurance

Purchase Context Estimated Price
With Insurance $1,000 – $3,000
Without Insurance (U.S.) $25,000 – $35,000
From Canada $22,000
Why Americans Buy Harvoni from Canada Pharmacy Store?

Why Americans Buy Harvoni from Canada Pharmacy Store?

Americans have trouble affording Harvoni due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
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Big Savings on U.S. Medications
Our customers save up to 80% on their Harvoni prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
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Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Harvoni prescriptions directly from your doctor or local pharmacy – completely free of charge.
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Direct Access to Experts

Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.

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Discreet U.S. Shipping

All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.

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Trusted by Americans Nationwide

With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.

How to Order Harvoni Online

How to Order Harvoni Online

Step 1

Select Your Prescribed Harvoni Dosage

Choose the strength and quantity as directed by your healthcare provider and add it to your cart.

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Step 2

Proceed Through Secure Checkout

Follow the steps to complete your order and provide necessary shipping and payment details.

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Step 3

Upload Your Harvoni Prescription

Submit a prescription from a licensed U.S. healthcare provider that matches your order.

At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.

Guarantee
Guarantee Certificate

Our Guarantee When You Buy Harvoni Through Canada Pharmacy Store

At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.

The Harvoni you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Harvoni at a lower price, simply place your order above or give us a call at 1-888-903-2240