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General Medication Fact Sheet for Indapamide
| Field | Information |
|---|---|
| Generic Name | Indapamide |
| Brand Name Versions | Lozol |
| Boxed/Label Warning | None |
| Purpose | Thiazide-like diuretic used to treat high blood pressure (hypertension) and edema. |
| Mechanism of Action | Inhibits sodium reabsorption in the distal convoluted tubule of the kidney, increasing sodium and water excretion and reducing blood volume. Also has vasodilatory effects. |
| Dosage Forms | Oral tablets |
| Available Strengths | 1.25 mg, 2.5 mg |
| Dosage Frequency | Typically once daily, or as directed by a healthcare provider. |
| Common Side Effects | Dizziness, lightheadedness, headache, weakness, fatigue, muscle cramps, nausea, constipation, dry mouth. |
| Serious Side Effects | Electrolyte imbalances (low sodium, potassium, magnesium), dehydration, kidney problems, allergic reactions (rash, itching, swelling, difficulty breathing), irregular heartbeat. |
| Drug Interactions | Other diuretics, ACE inhibitors, ARBs, digoxin, lithium, NSAIDs, corticosteroids. |
| Important Notes | May cause dizziness or lightheadedness; use caution when driving or operating machinery. Monitor electrolyte levels regularly. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Hydrochlorothiazide, Chlorthalidone, Furosemide, Lisinopril |
Indapamide Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Hydrochlorothiazide (Microzide) | Thiazide diuretic, inhibits sodium reabsorption in the distal convoluted tubule. | Commonly used diuretic for hypertension. |
| Chlorthalidone (Hygroton) | Thiazide-like diuretic, similar mechanism to Hydrochlorothiazide but longer duration of action. | Often preferred due to its longer half-life. |
| Furosemide (Lasix) | Loop diuretic, inhibits sodium and chloride reabsorption in the loop of Henle. | More potent diuretic, typically used for edema associated with heart failure or kidney disease. |
| Lisinopril (Prinivil, Zestril) | ACE inhibitor, blocks the conversion of angiotensin I to angiotensin II, leading to vasodilation. | Antihypertensive medication that works through a different mechanism. |
Indapamide Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | Electrolyte imbalances (low sodium, potassium, magnesium) |
| Lightheadedness | Dehydration |
| Headache | Kidney problems |
| Weakness | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Fatigue | Irregular heartbeat |
| Muscle cramps | Gout |
| Nausea | Pancreatitis |
| Constipation | Liver problems |
| Dry mouth | Vision changes |
Indapamide Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hypertension | 1.25 mg daily | 1.25 – 5 mg daily | Take in the morning. |
| Edema | 2.5 mg daily | 2.5 – 5 mg daily | Take in the morning. |
Indapamide Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 |
| Without Insurance (U.S.) | $15 |
| From Canada | $5 |
