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Inspiolto
| Stiolto Respimat Tiotropium Bromide Monohydrate, Olodaterol Hydrochloride | ||||||
Shipped from United Kingdom | ||||||
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General Medication Fact Sheet for Inspiolto
| Field | Information |
|---|---|
| Medication Name | Inspiolto |
| Generic Name | Tiotropium Bromide and Olodaterol |
| Purpose | Long-term, once-daily maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema. |
| Mechanism of Action | Tiotropium is a long-acting muscarinic antagonist (LAMA), and olodaterol is a long-acting beta2-adrenergic agonist (LABA). They work by relaxing the muscles around the airways in the lungs, making it easier to breathe. |
| Dosage Forms | Inhalation spray (Respimat inhaler) |
| Available Strengths | Tiotropium 2.5 mcg / Olodaterol 2.5 mcg per puff |
| Dosage Frequency | Once daily |
| Common Side Effects | Dry mouth, cough, blurred vision, constipation, urinary retention, upper respiratory tract infection. |
| Serious Side Effects | Paradoxical bronchospasm, acute narrow-angle glaucoma, urinary retention, hypersensitivity reactions (including anaphylaxis, angioedema, urticaria, rash), cardiovascular effects (such as palpitations, chest pain, arrhythmia). |
| Drug Interactions | Other anticholinergics, beta-adrenergic agonists, monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, potassium-depleting diuretics. |
| Important Notes | Inspiolto is not a rescue medication for sudden breathing problems. Always have a rescue inhaler available. Use with caution in patients with narrow-angle glaucoma, urinary retention, cardiovascular disorders, or seizure disorders. |
| Storage | Store at room temperature away from moisture and light. Keep the Respimat inhaler out of the reach of children. |
| Missed Dose | If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once. |
| Alternatives | Spiriva (tiotropium), Striverdi (olodaterol), Anoro Ellipta (umeclidinium/vilanterol), Incruse Ellipta (umeclidinium). |
Inspiolto Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Spiriva (tiotropium) | Long-acting muscarinic antagonist (LAMA) | A LAMA used for COPD; does not contain a LABA. |
| Striverdi (olodaterol) | Long-acting beta2-adrenergic agonist (LABA) | A LABA used for COPD; does not contain a LAMA. |
| Anoro Ellipta (umeclidinium/vilanterol) | LAMA/LABA combination | Another combination LAMA/LABA inhaler for COPD. |
| Incruse Ellipta (umeclidinium) | Long-acting muscarinic antagonist (LAMA) | LAMA monotherapy for COPD. |
Inspiolto Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dry mouth | Paradoxical bronchospasm |
| Cough | Acute narrow-angle glaucoma |
| Blurred vision | Urinary retention |
| Constipation | Hypersensitivity reactions (anaphylaxis, angioedema) |
| Upper respiratory tract infection | Cardiovascular effects (palpitations, chest pain, arrhythmia) |
Inspiolto Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| COPD | 2 puffs once daily | 2 puffs once daily | Administer as 2 puffs from the Respimat inhaler, once daily. Prime the inhaler before first use. |
Inspiolto Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $45 |
| Without Insurance (U.S.) | $190 |
| From Canada | $111.95 |
