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General Medication Fact Sheet for Ivermectin
| Field | Information |
|---|---|
| Generic Name | Ivermectin |
| Brand Name Versions | Stromectol, Sklice, Soolantra |
| Boxed/Label Warning | N/A |
| Purpose | Anti-parasitic medication used to treat certain parasitic infections and skin conditions like rosacea. |
| Mechanism of Action | Binds to glutamate-gated chloride ion channels in invertebrate nerve and muscle cells, causing paralysis and death of the parasite. |
| Dosage Forms | Oral tablets, topical cream, topical lotion |
| Available Strengths | 3 mg, 6 mg, 1% cream, 0.5% lotion |
| Dosage Frequency | Single dose for parasitic infections; daily for topical treatments, as directed by a healthcare provider. |
| Common Side Effects | Dizziness, nausea, diarrhea, itching (for oral); burning sensation, skin irritation (for topical) |
| Serious Side Effects | Seizures, coma, severe skin rash, liver problems (rare) |
| Drug Interactions | Warfarin (increased bleeding risk), other medications metabolized by CYP3A4 enzymes |
| Important Notes | Take on an empty stomach with water for oral administration; avoid alcohol; consult a doctor if side effects persist. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember for oral administration; apply topical medication as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Albendazole, Mebendazole, Permethrin (for some conditions) |
Ivermectin Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Albendazole | Inhibits tubulin polymerization, disrupting microtubule-dependent glucose uptake in susceptible helminths. | Used for various parasitic infections. |
| Mebendazole | Inhibits the formation of microtubules in worms, leading to immobilization and death. | Used for various parasitic infections. |
| Permethrin | Disrupts sodium channel currents in nerve cell membranes of arthropods. | Used for scabies and lice. |
Ivermectin Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | Seizures |
| Nausea | Coma |
| Diarrhea | Severe skin rash (e.g., Stevens-Johnson syndrome) |
| Itching (for oral) | Liver problems |
| Burning sensation (for topical) | Eye problems (rare) |
Ivermectin Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Strongyloidiasis | 200 mcg/kg | Single dose | Take on an empty stomach with water. |
| Onchocerciasis | 150 mcg/kg | Single dose, repeated every 6-12 months if needed | Take on an empty stomach with water. |
| Rosacea (topical) | Apply a pea-sized amount | Apply once daily | Apply to affected areas of the face, avoiding eyes and lips. |
Ivermectin Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $5 – $20 |
| Without Insurance (U.S.) | $25 – $75 |
| From Canada | $10 – $30 |
