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Januvia (Sitagliptin Phosphate)
| Sitagliptin (Generic) Sitagliptin | ||||||
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Shipped from Canada | ||||||
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General Medication Fact Sheet for Januvia
| Field | Information |
|---|---|
| Medication Name | Januvia |
| Generic Name | Sitagliptin |
| Boxed/Label Warning | (Rare) Severe joint pain |
| Purpose | Treatment of type 2 diabetes mellitus. |
| Mechanism of Action | DPP-4 inhibitor; increases incretin levels, which stimulate insulin release and decrease glucagon secretion. |
| Dosage Forms | Oral tablets |
| Available Strengths | 25 mg, 50 mg, 100 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Upper respiratory tract infection, stuffy or runny nose and sore throat, headache |
| Serious Side Effects | Pancreatitis, severe allergic reactions, kidney problems, severe joint pain, bullous pemphigoid. |
| Drug Interactions | Insulin, sulfonylureas (e.g., Glipizide, glyburide), digoxin. |
| Important Notes | May be taken with or without food. Monitor blood sugar levels regularly. Consult a healthcare provider for dose adjustments. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose. |
| Alternatives | Metformin, Glipizide, Jardiance (empagliflozin), Tradjenta (linagliptin) |
Januvia Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Metformin (Glucophage) | Biguanide; decreases hepatic glucose production and increases insulin sensitivity. | First-line treatment for type 2 diabetes. |
| Glipizide (Glucotrol) | Sulfonylurea; stimulates insulin release from pancreatic beta cells. | May cause hypoglycemia. |
| Jardiance (Empagliflozin) | SGLT2 inhibitor; reduces reabsorption of glucose in the kidney, increasing glucose excretion in the urine. | May cause urinary tract infections. |
| Tradjenta (Linagliptin) | DPP-4 inhibitor; similar mechanism to Januvia (sitagliptin). | Can be used without dose adjustment in patients with kidney problems. |
Januvia Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Upper respiratory tract infection | Pancreatitis |
| Stuffy or runny nose and sore throat | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
| Headache | Kidney problems |
| Nausea | Severe joint pain |
| Diarrhea | Bullous pemphigoid (a skin disorder) |
Januvia Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Type 2 Diabetes Mellitus | 25 mg, 50mg, or 100 mg once daily | 25 mg, 50mg, or 100 mg once daily | Dosage is individualized based on glycemic control and renal function. May be taken with or without food. |
| Type 2 Diabetes Mellitus (with renal impairment) | Adjusted based on creatinine clearance | Adjusted based on creatinine clearance | Consult a healthcare provider for proper dosage adjustment. |
Januvia Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 – $75 |
| Without Insurance (U.S.) | $500 – $600 |
| From Canada | $21.21 |
