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Keppra (Levetiracetam)
| Levetiracetam (Generic) Levetiracetam | ||||||
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Shipped from Canada | ||||||
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| Levetiracetam (Generic) Levetiracetam | ||||||
Shipped from United Kingdom | ||||||
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| Levetiracetam (Generic) Levetiracetam | ||||||
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Shipped from Mauritius | ||||||
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| Levetiracetam Liquid (Generic) Levetiracetam | ||||||
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Shipped from Canada | ||||||
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General Medication Fact Sheet for Keppra
| Field | Information |
|---|---|
| Medication Name | Keppra |
| Generic Name | Levetiracetam |
| Purpose | Antiepileptic medication used to treat seizures |
| Mechanism of Action | The exact mechanism is unknown, but it is believed to bind to synaptic vesicle protein 2A (SV2A), which may modulate neurotransmitter release. |
| Dosage Forms | Oral tablets, oral solution, intravenous (IV) solution |
| Available Strengths | 250 mg, 500 mg, 750 mg, 1000 mg (tablets); 100 mg/mL (oral solution); 100 mg/mL (IV solution) |
| Dosage Frequency | Typically twice daily, or as directed by a healthcare provider |
| Common Side Effects | Drowsiness, weakness, headache, dizziness, loss of appetite |
| Serious Side Effects | Mood changes, behavioral changes, depression, anxiety, suicidal thoughts, severe allergic reactions |
| Drug Interactions | Other antiepileptic drugs, central nervous system depressants (e.g., alcohol, sedatives) |
| Important Notes | Do not stop taking Keppra suddenly without consulting your doctor; may cause withdrawal seizures. Monitor for changes in mood or behavior. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Lamotrigine, Topiramate, Valproic Acid, Carbamazepine |
Keppra Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Lamotrigine (Lamictal) | Blocks voltage-sensitive sodium channels, stabilizes neuronal membranes, and inhibits the release of excitatory neurotransmitters. | Used for various seizure types and bipolar disorder. |
| Topiramate (Topamax) | Blocks sodium channels, enhances GABA activity, and inhibits glutamate activity. | Also used for migraine prevention. |
| Valproic Acid (Depakote) | Increases GABA concentrations, blocks sodium channels, and reduces T-type calcium currents. | Effective for a broad range of seizure types but has significant side effects. |
| Carbamazepine (Tegretol) | Blocks voltage-gated sodium channels. | Known for drug interactions. |
Keppra Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Drowsiness | Mood changes |
| Weakness | Behavioral changes |
| Headache | Depression |
| Dizziness | Anxiety |
| Loss of appetite | Suicidal thoughts |
| Nausea | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
Keppra Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Partial-Onset Seizures (Adults) | 500 mg twice daily | 1000 mg to 3000 mg daily, divided in two doses | Can be taken with or without food. |
| Partial-Onset Seizures (Children 4+ years) | 10 mg/kg twice daily | 20 mg/kg to 60 mg/kg daily, divided in two doses | Dose adjustments are based on weight. |
| Myoclonic Seizures (Adults and Adolescents 12+ years) | 500 mg twice daily | 1000 mg to 3000 mg daily, divided in two doses | Titrate gradually to minimize side effects. |
| Tonic-Clonic Seizures (Adults and Adolescents 6+ years) | 500 mg twice daily | 1000 mg to 3000 mg daily, divided in two doses | Monitor for seizure control and adjust dose accordingly. |
Keppra Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $30 |
| Without Insurance (U.S.) | $150 |
| From Canada | $50 |
