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Lamisil (Terbinafine)
| Terbinafine (Generic) Terbinafine Hydrochloride | ||||||
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Shipped from Canada | ||||||
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| Terbinafine (Generic) Terbinafine Hydrochloride | ||||||
Shipped from United Kingdom | ||||||
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| Terbinafine Cream (Generic) Terbinafine Hydrochloride | ||||||
Shipped from United Kingdom | ||||||
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General Medication Fact Sheet for Lamisil
| Field | Information |
|---|---|
| Medication Name | Lamisil |
| Generic Name | Terbinafine |
| Boxed/Label Warning | Rare cases of liver failure, some leading to liver transplant or death, have occurred with oral terbinafine. Monitor liver function. |
| Purpose | Antifungal medication used to treat fungal infections of the nails (onychomycosis) and skin (tinea infections). |
| Mechanism of Action | Inhibits squalene epoxidase, a key enzyme in fungal sterol biosynthesis, leading to fungal cell death. |
| Dosage Forms | Oral tablets, topical cream, topical gel, topical spray |
| Available Strengths | Oral tablets: 250 mg; Topical Cream/Gel/Spray: 1% |
| Dosage Frequency | Oral: Once daily. Topical: Usually twice daily, or as directed by a healthcare provider. |
| Common Side Effects | Headache, nausea, diarrhea, rash, itching, changes in taste. For topical formulations: redness, itching, burning. |
| Serious Side Effects | Liver problems (jaundice, dark urine, pale stools), severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), blood disorders (decreased white blood cell count). |
| Drug Interactions | Rifampin, cimetidine, certain antidepressants (SSRIs, TCAs), beta-blockers, warfarin. |
| Important Notes | Inform your doctor of any pre-existing liver conditions. Liver function tests may be monitored during oral terbinafine therapy. Avoid alcohol. |
| Storage | Store oral tablets at room temperature away from moisture and light. Store topical formulations as directed on the packaging. |
| Missed Dose | If you miss a dose of the oral tablet, take it as soon as you remember. If it is close to your next dose, skip the missed dose. Do not double the dose. For topical formulations, apply as soon as you remember and continue with your regular schedule. |
| Alternatives | Itraconazole, Fluconazole, Griseofulvin, Ciclopirox (topical). |
Lamisil Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Itraconazole (Sporanox) | Inhibits fungal ergosterol synthesis. | Oral antifungal used for various fungal infections. Requires monitoring for liver function. |
| Fluconazole (Diflucan) | Inhibits fungal ergosterol synthesis. | Oral antifungal used for various fungal infections. |
| Griseofulvin | Interferes with fungal cell mitosis. | Oral antifungal, older medication, may have more side effects. |
| Ciclopirox (Penlac, Loprox) | Interferes with fungal cell membrane transport. | Topical antifungal, often used for nail infections. |
Lamisil Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Liver problems (jaundice, dark urine, pale stools) |
| Nausea | Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) |
| Diarrhea | Blood disorders (decreased white blood cell count) |
| Rash | Allergic reactions (hives, difficulty breathing, swelling of the face, lips, tongue, or throat) |
| Itching | Changes in taste (or loss of taste) – usually reversible |
Lamisil Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Onychomycosis (Fingernail) | 250 mg | 250 mg once daily for 6 weeks | Take with or without food. |
| Onychomycosis (Toenail) | 250 mg | 250 mg once daily for 12 weeks | Take with or without food. |
| Tinea Infections (Topical) | Apply a thin layer | Apply a thin layer twice daily | Continue treatment for the recommended duration, even if symptoms improve. Consult with your healthcare provider if there is no improvement after 2 weeks. |
Lamisil Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 |
| Without Insurance (U.S.) | $40 |
| From Canada | $35 |
