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Lancora (Ivabradine)
| Ivabradine (Generic) Ivabradine | ||||||
Shipped from United Kingdom | ||||||
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| Ivabradine (Generic) Ivabradine | ||||||
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Shipped from Mauritius | ||||||
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Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Select product strength & quantity:
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General Medication Fact Sheet for Lancora
| Field | Information |
|---|---|
| Medication Name | Lancora |
| Generic Name | Ivabradine |
| Boxed/Label Warning | Ivabradine can cause fetal toxicity. Exclude pregnancy before starting and advise women of reproductive potential to use effective contraception. |
| Purpose | Reduces the risk of hospitalization for worsening heart failure due to chronic stable heart failure in patients with left ventricular ejection fraction ≤ 35% and resting heart rate ≥ 70 bpm. Also used to treat stable symptomatic heart failure. |
| Mechanism of Action | Selectively inhibits the If current in the sinoatrial (SA) node, which reduces the heart rate. |
| Dosage Forms | Oral tablets |
| Available Strengths | 5 mg, 7.5 mg |
| Dosage Frequency | Typically twice daily, with meals. |
| Common Side Effects | Bradycardia (slow heart rate), hypertension, atrial fibrillation, luminous phenomena (phosphenes) |
| Serious Side Effects | Severe bradycardia, heart block, syncope, atrial fibrillation |
| Drug Interactions | Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin), moderate CYP3A4 inhibitors (e.g., diltiazem, verapamil), CYP3A4 inducers (e.g., rifampin, St. John’s Wort), digoxin. |
| Important Notes | Monitor heart rate regularly. Avoid use in patients with severe liver impairment or sick sinus syndrome. Notify your doctor if you experience dizziness, fatigue, or palpitations. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Beta-blockers (e.g., Metoprolol, Bisoprolol), Digoxin, ACE inhibitors (e.g., Lisinopril), ARBs (e.g., Valsartan) |
Lancora Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Metoprolol (Lopressor, Toprol XL) | Beta-adrenergic blocker | Reduces heart rate and blood pressure. Commonly used for heart failure and hypertension. |
| Bisoprolol (Zebeta) | Beta-adrenergic blocker | Similar to metoprolol; used for heart failure and hypertension. |
| Digoxin (Lanoxin) | Cardiac glycoside | Increases the force of heart contraction and slows heart rate. |
| Lisinopril (Prinivil, Zestril) | ACE inhibitor | Reduces blood pressure and helps improve heart failure symptoms. |
| Valsartan (Diovan) | ARB (Angiotensin Receptor Blocker) | Alternative to ACE inhibitors, with similar effects on blood pressure and heart failure. |
Lancora Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Bradycardia (slow heart rate) | Severe bradycardia |
| Hypertension (high blood pressure) | Heart block |
| Atrial fibrillation | Syncope (fainting) |
| Luminous phenomena (phosphenes) | Significant worsening of heart failure |
| Dizziness | Atrial fibrillation |
Lancora Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Chronic Stable Heart Failure | 5 mg twice daily | Adjusted based on heart rate; range 2.5 mg to 7.5 mg twice daily | Take with meals. Monitor heart rate and blood pressure. |
