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General Medication Fact Sheet for Locoid
| Field | Information |
|---|---|
| Medication Name | Locoid |
| Generic Name | Hydrocortisone Butyrate |
| Purpose | Treatment of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. |
| Mechanism of Action | Corticosteroids bind to intracellular receptors, influencing protein synthesis and suppressing the immune response. |
| Dosage Forms | Cream, Ointment, Lotion |
| Available Strengths | 0.1% |
| Dosage Frequency | Apply a thin film to the affected skin areas two to four times daily. |
| Common Side Effects | Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin atrophy, secondary infection. |
| Serious Side Effects | Adrenal suppression, Cushing’s syndrome, hyperglycemia, glaucoma, cataracts. |
| Drug Interactions | No significant drug interactions reported; however, use caution with other topical medications. |
| Important Notes | For external use only. Avoid contact with eyes. Do not use on the face, underarms, or groin areas unless directed by a doctor. Do not bandage or cover the treated skin area unless told to do so by your doctor. Discontinue use if irritation develops. |
| Storage | Store at room temperature away from moisture and heat. Keep out of reach of children. |
| Missed Dose | Apply as soon as you remember. If it is almost time for your next dose, skip the missed dose and apply the next dose at the regularly scheduled time. Do not apply extra medicine to make up the missed dose. |
| Alternatives | Hydrocortisone, Betamethasone, Triamcinolone, Clobetasol |
Locoid Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Hydrocortisone (Cortaid) | Corticosteroid; reduces inflammation and immune response. | Lower potency; available over-the-counter for mild skin conditions. |
| Betamethasone (Diprolene) | Corticosteroid; reduces inflammation and immune response. | Higher potency; prescription required. |
| Triamcinolone (Kenalog) | Corticosteroid; reduces inflammation and immune response. | Medium potency; prescription required. |
| Clobetasol (Clobex, Temovate) | Corticosteroid; reduces inflammation and immune response. | Very high potency; use should be limited to two consecutive weeks. |
Locoid Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Burning | Adrenal suppression |
| Itching | Cushing’s syndrome |
| Irritation | Hyperglycemia |
| Dryness | Glaucoma |
| Folliculitis | Cataracts |
| Acneiform eruptions | Skin atrophy (thinning of the skin) |
Locoid Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Eczema | Apply a thin film | Apply a thin film two to four times daily | Apply to affected areas only. Rub in gently. |
| Dermatitis | Apply a thin film | Apply a thin film two to four times daily | Apply to affected areas only. Rub in gently. |
| Psoriasis | Apply a thin film | Apply a thin film two to four times daily | Apply to affected areas only. Rub in gently. |
Locoid Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 |
| Without Insurance (U.S.) | $50 |
| From Canada | $40 |
