Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Lorbrena
| Field | Information |
|---|---|
| Medication Name | Lorbrena |
| Generic Name | Lorlatinib |
| Purpose | Treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) whose disease has progressed on crizotinib and at least one other ALK inhibitor; or whose disease has progressed on alectinib or ceritinib as the first ALK inhibitor therapy. |
| Mechanism of Action | Lorlatinib is a kinase inhibitor that binds to and inhibits ALK, ROS1, TYK1, FER, FAK, TRKA, TRKB, TRKC, and EGFR. |
| Dosage Forms | Oral tablets |
| Available Strengths | 25 mg, 100 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Edema, peripheral neuropathy, cognitive effects, dyspnea, hypercholesterolemia, hypertriglyceridemia, weight gain, arthralgia, fatigue, diarrhea, mood disturbances |
| Serious Side Effects | Hyperlipidemia, central nervous system effects, pneumonitis, atrioventricular (AV) block, hypertension, hyperglycemia, increased lipase and/or amylase |
| Drug Interactions | Strong CYP3A inducers (e.g., rifampin, phenytoin), CYP3A substrates, P-gp substrates |
| Important Notes | Monitor lipid levels regularly. Assess for CNS effects and peripheral neuropathy. Females of reproductive potential should use effective contraception. |
| Storage | Store at room temperature between 68°F to 77°F (20°C to 25°C). |
| Missed Dose | Take as soon as you remember unless it is less than 4 hours until your next dose. Do not double the dose. |
| Alternatives | Alectinib (Alecensa), Ceritinib (Zykadia), Brigatinib (Alunbrig), Crizotinib (Xalkori) |
Lorbrena Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Alectinib (Alecensa) | ALK and RET inhibitor | Used as first-line treatment in ALK-positive NSCLC. |
| Ceritinib (Zykadia) | ALK inhibitor | Used in patients who have progressed on or are intolerant to crizotinib. |
| Brigatinib (Alunbrig) | ALK and EGFR inhibitor | Effective in patients resistant to crizotinib. |
| Crizotinib (Xalkori) | ALK, ROS1, and MET inhibitor | First-generation ALK inhibitor, often used as initial therapy. |
Lorbrena Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Edema | Hyperlipidemia |
| Peripheral Neuropathy | Central Nervous System Effects (cognitive effects, mood disturbances) |
| Cognitive Effects | Pneumonitis |
| Dyspnea | Atrioventricular (AV) Block |
| Hypercholesterolemia | Hypertension |
| Hypertriglyceridemia | Hyperglycemia |
| Weight Gain | Increased Lipase and/or Amylase |
| Arthralgia | Lung problems: new or worsening cough, shortness of breath, chest pain |
Lorbrena Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| ALK-Positive Metastatic NSCLC | 100 mg | 100 mg once daily | Swallow whole. Can be taken with or without food. |
Lorbrena Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25,000 |
| Without Insurance (U.S.) | $32,000 |
| From Canada | $24,000 |
Why Americans Buy Lorbrena from Canada Pharmacy Store?
Why Americans Buy Lorbrena from Canada Pharmacy Store?
Americans have trouble affording Lorbrena due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Lorbrena prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Lorbrena prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Lorbrena Online
How to Order Lorbrena Online
Step 1
Select Your Prescribed Lorbrena Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Lorbrena Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Lorbrena Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Lorbrena you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Lorbrena at a lower price, simply place your order above or give us a call at 1-888-903-2240
Viewers Also Liked
