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Macrobid (Nitrofurantoin)
| Nitrofurantoin Macrocrystals (Generic) Nitrofurantoin Macrocrystals | ||||||
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Shipped from Canada | ||||||
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General Medication Fact Sheet for Macrobid
| Field | Information |
|---|---|
| Medication Name | Macrobid |
| Generic Name | Nitrofurantoin monohydrate/macrocrystals |
| Boxed/Label Warning | Nitrofurantoin should not be used to treat kidney infections or other infections beyond the bladder. |
| Purpose | Antibiotic used to treat urinary tract infections (UTIs) |
| Mechanism of Action | Damages bacterial DNA, inhibiting bacterial growth and reproduction in the urinary tract |
| Dosage Forms | Oral capsules |
| Available Strengths | 100 mg |
| Dosage Frequency | Typically twice daily for 7 days, or as directed by a healthcare provider |
| Common Side Effects | Nausea, vomiting, loss of appetite, diarrhea, headache |
| Serious Side Effects | Pulmonary reactions (cough, shortness of breath), liver problems (jaundice, abdominal pain), peripheral neuropathy (numbness, tingling), severe allergic reactions |
| Drug Interactions | Antacids containing magnesium trisilicate, probenecid, quinolone antibiotics |
| Important Notes | Take with food to enhance absorption; complete the full course of treatment; report any signs of lung or liver problems to your doctor immediately |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Fosfomycin, Trimethoprim/Sulfamethoxazole (Bactrim), Ciprofloxacin (Cipro), Cephalexin (Keflex) |
Macrobid Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Fosfomycin (Monurol) | Inhibits bacterial cell wall synthesis | Single-dose oral treatment for uncomplicated UTIs. |
| Trimethoprim/Sulfamethoxazole (Bactrim) | Inhibits bacterial folate synthesis | Commonly used, but resistance is increasing in some areas. |
| Ciprofloxacin (Cipro) | Inhibits bacterial DNA gyrase | Fluoroquinolone antibiotic; use should be limited due to potential side effects. |
| Cephalexin (Keflex) | Inhibits bacterial cell wall synthesis | Cephalosporin antibiotic; another alternative for UTIs. |
Macrobid Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Pulmonary reactions (cough, shortness of breath) |
| Vomiting | Liver problems (jaundice, abdominal pain) |
| Loss of appetite | Peripheral neuropathy (numbness, tingling) |
| Diarrhea | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
| Headache | Persistent cough or fever |
Macrobid Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Uncomplicated UTI | 100 mg | 100 mg twice daily for 7 days | Take with food. Complete the full course of treatment. |
Macrobid Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 |
| Without Insurance (U.S.) | $25 |
| From Canada | $20 |
