Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Malarone(Atovaquone + Proguanil)
| Atovaquone/proguanil (Generic) Atovaquone, Proguanil Hydrochloride | ||||||
Shipped from United Kingdom | ||||||
| | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
General Medication Fact Sheet for Malarone
| Field | Information |
|---|---|
| Medication Name | Malarone |
| Generic Name | Atovaquone/Proguanil |
| Purpose | Antimalarial medication used for the prevention and treatment of malaria. |
| Mechanism of Action | Atovaquone disrupts mitochondrial electron transport in parasites, and proguanil inhibits dihydrofolate reductase, disrupting DNA synthesis. |
| Dosage Forms | Oral tablets |
| Available Strengths | Atovaquone 250mg / Proguanil 100mg (adult); Atovaquone 62.5mg / Proguanil 25mg (pediatric) |
| Dosage Frequency | Once daily |
| Common Side Effects | Headache, abdominal pain, nausea, diarrhea |
| Serious Side Effects | Allergic reactions (rash, itching, swelling, difficulty breathing), severe abdominal pain, jaundice (yellowing of the skin or eyes) |
| Drug Interactions | Tetracycline, metoclopramide, rifampin, warfarin, indinavir |
| Important Notes | Take with food or a milky drink to increase absorption; start 1-2 days before entering malaria area, continue during stay, and for 7 days after leaving. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; continue with your regular dosing schedule. |
| Alternatives | Doxycycline, Mefloquine, Chloroquine, Primaquine |
Malarone Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Doxycycline | Inhibits bacterial protein synthesis | Broad-spectrum antibiotic also effective as an antimalarial. Must avoid prolonged sun exposure. |
| Mefloquine | Unknown; thought to disrupt parasite membranes | Can cause neuropsychiatric side effects. |
| Chloroquine | Interferes with parasite’s digestive vacuole | Resistance is widespread; only effective in certain regions. |
| Primaquine | Disrupts parasite mitochondria and DNA | Used for terminal prophylaxis, eliminating liver stages of the parasite. Must be tested for G6PD deficiency before use. |
Malarone Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Abdominal pain | Severe abdominal pain |
| Nausea | Jaundice (yellowing of the skin or eyes) |
| Diarrhea | Seizures |
| Cough | Psychiatric disturbances (anxiety, depression, hallucinations) |
Malarone Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Malaria Prevention (Adults) | 1 tablet daily | 1 tablet daily | Start 1-2 days before entering malaria area, continue during stay, and for 7 days after leaving. Take with food or a milky drink. |
| Malaria Prevention (Children, based on weight) | Varies by weight | Varies by weight | Start 1-2 days before entering malaria area, continue during stay, and for 7 days after leaving. Take with food or a milky drink. Refer to prescribing information for specific weight-based dosing. |
| Malaria Treatment (Adults) | 4 tablets once daily for 3 days | N/A | Take with food. |
Malarone Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 |
| Without Insurance (U.S.) | $95 |
| From Canada | $45 |
