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General Medication Fact Sheet for Minocycline
| Field | Information |
|---|---|
| Generic Name | Minocycline |
| Brand Name Versions | Minocin, Dynacin, Solodyn |
| Boxed/Label Warning | Minocycline can cause permanent tooth discoloration, especially in children under 8 years old. It can also cause autoimmune-like syndrome. |
| Purpose | Tetracycline antibiotic used to treat bacterial infections and acne. |
| Mechanism of Action | Inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. |
| Dosage Forms | Oral capsules, tablets, extended-release tablets |
| Available Strengths | 50 mg, 75 mg, 100 mg, 115 mg, 135 mg |
| Dosage Frequency | Typically once or twice daily, as directed by a healthcare provider. |
| Common Side Effects | Dizziness, vertigo, nausea, vomiting, diarrhea, skin discoloration. |
| Serious Side Effects | Autoimmune-like syndrome, liver problems, lupus-like syndrome, severe allergic reactions (anaphylaxis), increased intracranial pressure. |
| Drug Interactions | Antacids containing aluminum, calcium, or magnesium; iron supplements; bismuth subsalicylate (Pepto-Bismol); warfarin. |
| Important Notes | Take on an empty stomach, at least 1 hour before or 2 hours after meals. May cause photosensitivity (increased sensitivity to sunlight). |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Doxycycline, Tetracycline, Erythromycin, Azithromycin. |
Minocycline Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Doxycycline | Inhibits bacterial protein synthesis. | Another Tetracycline antibiotic; often used for acne and various infections. |
| Tetracycline | Inhibits bacterial protein synthesis. | A broad-spectrum antibiotic; similar to minocycline but may have different side effect profiles. |
| Erythromycin | Inhibits bacterial protein synthesis. | A macrolide antibiotic; an alternative for individuals with Tetracycline allergies. |
| Azithromycin (Zithromax) | Inhibits bacterial protein synthesis. | A macrolide antibiotic with a longer half-life than Erythromycin, allowing for shorter treatment courses. |
Minocycline Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | Autoimmune-like syndrome |
| Vertigo | Liver problems |
| Nausea | Lupus-like syndrome |
| Vomiting | Severe allergic reactions (anaphylaxis) |
| Diarrhea | Increased intracranial pressure (pseudotumor cerebri) |
| Skin discoloration | Permanent tooth discoloration (in children) |
Minocycline Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Acne | 50-100 mg | 50-100 mg once or twice daily | Take on an empty stomach. |
| Bacterial Infections | 200 mg | 100 mg every 12 hours | Take on an empty stomach. Follow healthcare provider’s instructions. |
Minocycline Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 |
| Without Insurance (U.S.) | $78 |
| From Canada | $34.95 |
