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General Medication Fact Sheet for Monoprost
| Field | Information |
|---|---|
| Medication Name | Monoprost |
| Generic Name | Latanoprost |
| Boxed/Label Warning | Increased brown iris pigmentation; gradual changes to eyelashes and vellus hair |
| Purpose | Reduces intraocular pressure in open-angle glaucoma or ocular hypertension |
| Mechanism of Action | Prostaglandin F2α analogue; increases uveoscleral outflow of aqueous humor |
| Dosage Forms | Ophthalmic solution (eye drops) |
| Available Strengths | 0.005% |
| Dosage Frequency | Once daily in the evening |
| Common Side Effects | Blurred vision, eye redness, itching, stinging, foreign body sensation, increased iris pigmentation |
| Serious Side Effects | Macular edema, uveitis, herpetic keratitis, paradoxical increase in intraocular pressure |
| Drug Interactions | Thimerosal-containing eye drops (administer separately); other prostaglandin analogs (use with caution) |
| Important Notes | Remove contact lenses before use; wait 15 minutes before reinserting. Use caution in patients with aphakia or pseudophakia. |
| Storage | Store unopened bottles in the refrigerator; once opened, store at room temperature away from light |
| Missed Dose | Administer as soon as remembered; if it is almost time for the next dose, skip the missed dose and administer the next dose at the regular time. Do not double the dose. |
| Alternatives | Travoprost (Travatan), Bimatoprost (Lumigan), Tafluprost (Zioptan), Timolol |
Monoprost Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Travoprost (Travatan) | Prostaglandin F2α analogue; increases uveoscleral outflow | Similar efficacy and side effects to Latanoprost. |
| Bimatoprost (Lumigan) | Prostamide analogue; increases uveoscleral outflow | May cause more pronounced eyelash growth. |
| Tafluprost (Zioptan) | Prostaglandin F2α analogue; increases uveoscleral outflow | Preservative-free formulation. |
| Timolol (Timoptic) | Beta-adrenergic blocker; decreases aqueous humor production | Alternative mechanism of action. May have systemic side effects. |
Monoprost Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Blurred vision | Macular edema |
| Eye redness | Uveitis |
| Itching | Herpetic keratitis |
| Stinging | Paradoxical increase in intraocular pressure |
| Foreign body sensation | Increased brown iris pigmentation (permanent) |
Monoprost Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Open-angle Glaucoma | One drop | One drop daily in the affected eye(s) | Administer in the evening. Avoid contact between the dropper and eye or surrounding structures. |
| Ocular Hypertension | One drop | One drop daily in the affected eye(s) | Administer in the evening. If using other topical ophthalmic medications, administer at least five minutes apart. |
Monoprost Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $50 – $200 |
| Without Insurance (U.S.) | $120 – $420 |
| From Canada | $30.50 |
