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Necon (Norethindrone, Ethinyl Estradiol)
| Ethinyl Estradiol/Norethindrone (Generic) Ethinyl Estradiol, Norethindrone | ||||||
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General Medication Fact Sheet for Necon
| Field | Information |
|---|---|
| Medication Name | Necon |
| Generic Name | Norethindrone and Ethinyl Estradiol |
| Purpose | Oral contraceptive used to prevent pregnancy. May also be used to treat acne, regulate menstrual cycles, and reduce the risk of ovarian cysts. |
| Mechanism of Action | Inhibits ovulation by suppressing gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone (FSH), and luteinizing hormone (LH). Also thickens cervical mucus, making it more difficult for sperm to reach the egg. Alters the endometrial lining to prevent implantation. |
| Dosage Forms | Oral tablets |
| Available Strengths | 0.5/35 (0.5 mg norethindrone/35 mcg ethinyl estradiol), 1/35 (1 mg norethindrone/35 mcg ethinyl estradiol) |
| Dosage Frequency | One tablet daily, at the same time each day. |
| Common Side Effects | Nausea, vomiting, headache, bloating, breast tenderness, weight changes, mood changes, spotting between periods. |
| Serious Side Effects | Blood clots (deep vein thrombosis, pulmonary embolism, stroke, heart attack), liver problems, high blood pressure, gallbladder disease, depression, vision changes. |
| Drug Interactions | Certain antibiotics (e.g., rifampin), antifungals (e.g., griseofulvin), anticonvulsants (e.g., phenytoin, carbamazepine), HIV protease inhibitors, St. John’s Wort. |
| Important Notes | Smoking increases the risk of serious cardiovascular side effects, especially in women over 35. Consult a doctor if you have a history of blood clots, heart disease, liver disease, or certain cancers. May reduce the effectiveness of certain medications. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take the missed pill as soon as you remember. If you miss two pills in a row, take two pills for two days. Use backup contraception (e.g., condoms) for seven days. |
| Alternatives | Ortho Tri-Cyclen, Loestrin, Yasmin, Apri, Sprintec |
Necon Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Ortho Tri-Cyclen (norgestimate/ethinyl estradiol) | Inhibits ovulation, thickens cervical mucus, alters endometrial lining. | Triphasic oral contraceptive. |
| Loestrin (norethindrone acetate/ethinyl estradiol) | Inhibits ovulation, thickens cervical mucus, alters endometrial lining. | Lower dose of estrogen. |
| Yasmin (drospirenone/ethinyl estradiol) | Inhibits ovulation, thickens cervical mucus, alters endometrial lining. | Contains drospirenone, a progestin with anti-androgenic properties. |
| Apri (desogestrel/ethinyl estradiol) | Inhibits ovulation, thickens cervical mucus, alters endometrial lining. | Monophasic oral contraceptive. |
| Sprintec (norgestimate/ethinyl estradiol) | Inhibits ovulation, thickens cervical mucus, alters endometrial lining. | Monophasic oral contraceptive. |
Necon Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Blood clots (DVT, PE, stroke, heart attack) |
| Headache | Liver problems |
| Bloating | High blood pressure |
| Breast tenderness | Gallbladder disease |
| Weight changes | Depression |
| Mood changes | Vision changes |
| Spotting between periods | Increased risk of certain cancers (e.g., breast, cervical) |
Necon Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Contraception | One tablet daily | One tablet daily | Start on the first Sunday after your period starts, or as directed by your doctor. Take at the same time each day. |
| Acne | One tablet daily | One tablet daily | Use as directed by your doctor, in conjunction with other acne treatments if necessary. |
| Menstrual Cycle Regulation | One tablet daily | One tablet daily | Take continuously for 21 days, followed by 7 days of placebo pills or no pills (depending on the specific product). |
Necon Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $30 |
| Without Insurance (U.S.) | $60 – $220 |
| From CPS | $51 |
