Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Neupro
| Field | Information |
|---|---|
| Medication Name | Neupro |
| Generic Name | Rotigotine |
| Boxed/Label Warning | May cause or worsen pre-existing dyskinesia (involuntary muscle movements) and psychosis-like behavior. Risk of skin reactions at application site. |
| Purpose | Treats Parkinson’s disease and Restless Legs Syndrome (RLS) |
| Mechanism of Action | Dopamine agonist; stimulates dopamine receptors in the brain |
| Dosage Forms | Transdermal patch |
| Available Strengths | 1 mg/24 hr, 2 mg/24 hr, 3 mg/24 hr, 4 mg/24 hr, 6 mg/24 hr, 8 mg/24 hr |
| Dosage Frequency | Applied once daily |
| Common Side Effects | Application site reactions (redness, itching), nausea, drowsiness, dizziness, headache, insomnia |
| Serious Side Effects | Dyskinesia, hallucinations, sudden sleep onset, orthostatic hypotension (low blood pressure), impulse control disorders (e.g., compulsive gambling, hypersexuality) |
| Drug Interactions | Antipsychotics, dopamine antagonists, metoclopramide, other CNS depressants (e.g., alcohol, benzodiazepines) |
| Important Notes | Rotate application sites daily to avoid skin irritation. Avoid external heat sources on the patch. Monitor for changes in behavior or mood. Do not abruptly discontinue medication. |
| Storage | Store in the refrigerator (2°C – 8°C/36°F – 46°F) until use. Store in the original packaging to protect from light. |
| Missed Dose | Apply a new patch as soon as you remember. Apply the new patch at your regular time the next day. Do not apply two patches at the same time to make up for a missed dose. |
| Alternatives | Pramipexole (Mirapex), Ropinirole (Requip), Levodopa/Carbidopa (Sinemet), Apomorphine (Apokyn) |
Neupro Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Pramipexole (Mirapex) | Dopamine agonist | Oral medication for Parkinson’s disease and RLS. |
| Ropinirole (Requip) | Dopamine agonist | Oral medication for Parkinson’s disease and RLS. |
| Levodopa/Carbidopa (Sinemet) | Dopamine precursor | Oral medication that converts to dopamine in the brain; primarily for Parkinson’s disease. |
| Apomorphine (Apokyn) | Dopamine agonist | Injectable medication for acute, intermittent treatment of “off” episodes in Parkinson’s disease. |
Neupro Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Application site reactions (redness, itching) | Dyskinesia (involuntary muscle movements) |
| Nausea | Hallucinations |
| Drowsiness | Sudden sleep onset |
| Dizziness | Orthostatic hypotension (low blood pressure) |
| Headache | Impulse control disorders (e.g., compulsive gambling, hypersexuality) |
| Insomnia | Neuroleptic Malignant Syndrome (NMS) -like symptoms with dose reduction or withdrawal |
Neupro Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Parkinson’s Disease | 2 mg/24 hr | May be increased weekly in 2 mg/24 hr increments to a maximum of 8 mg/24 hr | Apply to clean, dry, intact skin on the abdomen, thigh, hip, flank, shoulder, or upper arm. Rotate sites daily. |
| Restless Legs Syndrome (RLS) | 1 mg/24 hr | May be increased weekly in 1 mg/24 hr increments to a maximum of 3 mg/24 hr | Apply to clean, dry, intact skin on the abdomen, thigh, hip, flank, shoulder, or upper arm. Rotate sites daily. |
Neupro Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $300 |
| Without Insurance (U.S.) | $1,200 – $2,200 |
| From CPS | $174.95 |

