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Nitrolingual Pumpspray (Nitroglycerin)
| Nitroglycerin Pumpspray (Generic) Nitroglycerin | ||||||
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Shipped from Canada | ||||||
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General Medication Fact Sheet for Nitrolingual Pumpspray
| Field | Information |
|---|---|
| Medication Name | Nitrolingual Pumpspray |
| Generic Name | Nitroglycerin |
| Purpose | Relief of acute anginal attacks due to coronary artery disease. |
| Mechanism of Action | Vasodilator; relaxes vascular smooth muscle, resulting in dilation of peripheral arteries and veins, reducing preload and afterload on the heart. |
| Dosage Forms | Sublingual spray |
| Available Strengths | 0.4 mg/metered spray |
| Dosage Frequency | 1-2 sprays under the tongue as needed for chest pain. May repeat every 5 minutes, up to a maximum of 3 doses in 15 minutes. |
| Common Side Effects | Headache, dizziness, lightheadedness, flushing. |
| Serious Side Effects | Severe hypotension, paradoxical bradycardia, increased angina. |
| Drug Interactions | Phosphodiesterase-5 (PDE5) inhibitors (e.g., sildenafil, tadalafil), riociguat, ergot alkaloids. |
| Important Notes | Do not shake the spray. Prime the pump before first use or after prolonged periods of disuse. Seek immediate medical attention if chest pain is not relieved after 3 doses. |
| Storage | Store at room temperature, away from heat and light. Keep the container tightly closed. |
| Missed Dose | Nitrolingual Pumpspray is used as needed for chest pain. There is no scheduled dosing. |
| Alternatives | Nitroglycerin sublingual tablets, Isosorbide dinitrate, Isosorbide mononitrate, Ranolazine |
Nitrolingual Pumpspray Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Nitroglycerin Sublingual Tablets | Vasodilator; relaxes vascular smooth muscle. | A common alternative for quick relief of angina. |
| Isosorbide dinitrate (Isordil) | Vasodilator; relaxes vascular smooth muscle. | Longer-acting nitrate, often used for prophylaxis. |
| Isosorbide Mononitrate (Imdur) | Vasodilator; relaxes vascular smooth muscle. | Longer-acting nitrate, typically given once daily. |
| Ranolazine (Ranexa) | Inhibits the late sodium current in heart muscle cells. | Used to treat chronic angina; does not affect heart rate or blood pressure significantly. |
Nitrolingual Pumpspray Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Severe hypotension |
| Dizziness | Paradoxical bradycardia |
| Lightheadedness | Increased angina |
| Flushing | Allergic reaction (rash, itching, swelling, difficulty breathing) |
| Burning or tingling under the tongue | Fainting |
Nitrolingual Pumpspray Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Angina Pectoris (Acute Attack) | 1-2 sprays (0.4-0.8 mg) | 1-2 sprays (0.4-0.8 mg) as needed | Spray under the tongue. Do not inhale. Close mouth immediately after each spray. Repeat every 5 minutes up to 3 doses. Seek immediate medical attention if pain persists. |
Nitrolingual Pumpspray Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $20 – $50 |
| Without Insurance (U.S.) | $130 – $350 |
| From CPS | $21.95 |
