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General Medication Fact Sheet for Norfloxacin
| Field | Information |
|---|---|
| Generic Name | Norfloxacin |
| Brand Name Versions | Noroxin |
| Purpose | Treats bacterial infections, including urinary tract infections (UTIs), prostatitis, and some sexually transmitted infections. |
| Mechanism of Action | Inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. |
| Dosage Forms | Oral tablets |
| Available Strengths | 400 mg |
| Dosage Frequency | Typically twice daily, or as directed by a healthcare provider. |
| Common Side Effects | Nausea, headache, dizziness, abdominal pain. |
| Serious Side Effects | Tendon rupture, peripheral neuropathy, central nervous system effects (seizures, psychosis), heart rhythm problems. |
| Drug Interactions | Antacids containing magnesium or aluminum, NSAIDs, theophylline, warfarin, certain antiarrhythmics. |
| Important Notes | Avoid taking with dairy products or antacids. Stay hydrated. May increase sensitivity to sunlight. Consult a doctor if you have a history of seizures or heart problems. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Ciprofloxacin, Levofloxacin, Trimethoprim/Sulfamethoxazole (Bactrim) |
Norfloxacin Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Ciprofloxacin (Cipro) | Inhibits bacterial DNA gyrase and topoisomerase IV. | Another fluoroquinolone antibiotic with a similar spectrum of activity. |
| Levofloxacin (Levaquin) | Inhibits bacterial DNA gyrase and topoisomerase IV. | Another fluoroquinolone antibiotic with a similar spectrum of activity. |
| Trimethoprim/Sulfamethoxazole (Bactrim) | Inhibits bacterial folic acid synthesis. | A combination antibiotic often used for UTIs. |
Norfloxacin Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Tendon rupture |
| Headache | Peripheral neuropathy (nerve damage) |
| Dizziness | Central nervous system effects (seizures, psychosis) |
| Abdominal pain | Heart rhythm problems (QT prolongation) |
| Diarrhea | Allergic reactions (rash, itching, swelling, difficulty breathing) |
Norfloxacin Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Urinary Tract Infections (UTIs) | 400 mg | 400 mg twice daily for 3-10 days | Take with plenty of water. Avoid dairy products or antacids within 2 hours. |
| Prostatitis | 400 mg | 400 mg twice daily for 28 days | Take with plenty of water. Avoid dairy products or antacids within 2 hours. |
| Gonorrhea | 800 mg | Single dose | Take with plenty of water. Avoid dairy products or antacids within 2 hours. |
Norfloxacin Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $60 |
| Without Insurance (U.S.) | $20 – $80 |
| From CPS | $57.95 |
