Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Ofev
| Field | Information |
|---|---|
| Medication Name | Ofev |
| Generic Name | Nintedanib |
| Boxed/Label Warning | Potential risk of serious liver problems, increased risk of bleeding, gastrointestinal perforations, and embryo-fetal toxicity. |
| Purpose | Treatment of idiopathic pulmonary fibrosis (IPF), systemic sclerosis-associated interstitial lung disease (SSc-ILD), and chronic fibrosing interstitial lung diseases with a progressive phenotype. |
| Mechanism of Action | Tyrosine kinase inhibitor that blocks multiple growth factor receptors involved in fibrosis. |
| Dosage Forms | Oral capsules |
| Available Strengths | 100 mg, 150 mg |
| Dosage Frequency | Twice daily |
| Common Side Effects | Diarrhea, nausea, abdominal pain, vomiting, decreased appetite, weight loss, headache, and elevated liver enzymes. |
| Serious Side Effects | Liver damage, bleeding problems, gastrointestinal perforation, arterial thromboembolic events, embryo-fetal toxicity, and increased risk of heart attack or stroke. |
| Drug Interactions | CYP3A4 inhibitors (e.g., ketoconazole) may increase nintedanib levels; CYP3A4 inducers (e.g., rifampin) may decrease nintedanib levels; anticoagulants may increase bleeding risk. |
| Important Notes | Administer with food. Monitor liver function regularly. Women of childbearing potential should use effective contraception. Consult a healthcare provider before taking any other medications or supplements. |
| Storage | Store at room temperature between 68°F to 77°F (20°C to 25°C). Protect from moisture. |
| Missed Dose | Take the missed dose as soon as you remember, unless it is less than 6 hours until your next scheduled dose. Do not take two doses at the same time. |
| Alternatives | Esbriet (pirfenidone), immunosuppressants (e.g., azathioprine, mycophenolate), corticosteroids (e.g., prednisone) |
Ofev Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Esbriet (pirfenidone) | Reduces fibrosis by affecting multiple pathways, including TGF-beta and TNF-alpha. | Used for IPF. May cause photosensitivity. |
| azathioprine | Immunosuppressant that inhibits purine synthesis. | Used in some ILDs, can increase risk of infection. |
| Mycophenolate Mofetil (CellCept) | Immunosuppressant that inhibits purine synthesis. | Used in some ILDs, requires regular blood monitoring. |
| Prednisone | Corticosteroid with anti-inflammatory and immunosuppressant properties. | Used in some ILDs, long-term use associated with numerous side effects. |
Ofev Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Diarrhea | Liver damage |
| Nausea | Bleeding problems |
| Abdominal pain | Gastrointestinal perforation |
| Vomiting | Arterial thromboembolic events (heart attack, stroke) |
| Decreased appetite | Embryo-fetal toxicity |
| Weight loss | Increased risk of heart attack or stroke |
Ofev Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Idiopathic Pulmonary Fibrosis (IPF) | 150 mg twice daily | 150 mg twice daily | Administer with food. Reduce dose to 100 mg twice daily if side effects occur. |
| Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD) | 150 mg twice daily | 150 mg twice daily | Administer with food. Reduce dose to 100 mg twice daily if side effects occur. |
| Chronic Fibrosing Interstitial Lung Diseases with a Progressive Phenotype | 150 mg twice daily | 150 mg twice daily | Administer with food. Reduce dose to 100 mg twice daily if side effects occur. |
Ofev Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $250 |
| Without Insurance (U.S.) | $9000 – $9,500 |
| From CPS | $2,685.35 |
Why Americans Buy Ofev from Canada Pharmacy Store?
Why Americans Buy Ofev from Canada Pharmacy Store?
Americans have trouble affording Ofev due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Ofev prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Ofev prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Ofev Online
How to Order Ofev Online
Step 1
Select Your Prescribed Ofev Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Ofev Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Ofev Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Ofev you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Ofev at a lower price, simply place your order above or give us a call at 1-888-903-2240
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