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General Medication Fact Sheet for Onbrez Breezhaler
| Field | Information |
|---|---|
| Medication Name | Onbrez Breezhaler |
| Generic Name | Indacaterol |
| Purpose | Long-acting beta2-adrenergic agonist (LABA) used for long-term maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD). |
| Mechanism of Action | Relaxes bronchial smooth muscle by selectively stimulating beta2-adrenergic receptors, leading to bronchodilation. |
| Dosage Forms | Inhalation powder in capsules for use with the Breezhaler inhaler. |
| Available Strengths | 150 mcg, 300 mcg |
| Dosage Frequency | Once daily |
| Common Side Effects | Cough, upper respiratory tract infection, muscle spasms, chest pain, dizziness, headache, nausea. |
| Serious Side Effects | Paradoxical bronchospasm, increased heart rate, high blood pressure, hypokalemia, hyperglycemia, allergic reactions. |
| Drug Interactions | Other long-acting beta2-adrenergic agonists (LABAs), beta-blockers, diuretics, monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants. |
| Important Notes | Not for use in asthma without an inhaled corticosteroid; do not use for acute bronchospasm; rinse mouth after inhalation. |
| Storage | Store at room temperature away from moisture and light; keep capsules in blister pack until use. |
| Missed Dose | Take as soon as you remember unless it is almost time for your next dose; do not take a double dose. |
| Alternatives | Spiriva (tiotropium), Incruse Ellipta (umeclidinium), Serevent (salmeterol), Foradil (formoterol) |
Onbrez Breezhaler Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Spiriva (tiotropium) | Long-acting muscarinic antagonist (LAMA) | Another once-daily inhaled medication for COPD. |
| Incruse Ellipta (umeclidinium) | Long-acting muscarinic antagonist (LAMA) | Once-daily inhaled medication for COPD; available as a single agent or in combination with a LABA. |
| Serevent (salmeterol) | Long-acting beta2-adrenergic agonist (LABA) | A LABA similar to indacaterol but administered twice daily. |
| Foradil (formoterol) | Long-acting beta2-adrenergic agonist (LABA) | Another LABA option, available in various formulations. |
Onbrez Breezhaler Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Cough | Paradoxical bronchospasm |
| Upper respiratory tract infection | Increased heart rate |
| Muscle spasms | High blood pressure |
| Chest pain | Hypokalemia |
| Dizziness | Hyperglycemia |
| Headache | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Nausea | QTc prolongation |
Onbrez Breezhaler Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| COPD | 150 mcg | 150 mcg or 300 mcg once daily | Inhale the contents of one capsule using the Breezhaler inhaler; do not swallow the capsule. |
Onbrez Breezhaler Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $ |
| Without Insurance (U.S.) | $ |
| From CPS | $ |
