Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Ondansetron
| Field | Information |
|---|---|
| Generic Name | Ondansetron |
| Brand Name Versions | Zofran |
| Purpose | Prevention of nausea and vomiting |
| Mechanism of Action | Selective 5-HT3 receptor antagonist |
| Dosage Forms | Oral tablets, oral solution, intravenous injection |
| Available Strengths | 4 mg, 8 mg |
| Dosage Frequency | Typically three times a day, or as directed by a healthcare provider |
| Common Side Effects | Headache, constipation, diarrhea, dizziness |
| Serious Side Effects | Serotonin syndrome, irregular heartbeats (QT prolongation), blurred vision |
| Drug Interactions | Apomorphine, tramadol, certain antidepressants (SSRIs, SNRIs), antiarrhythmics |
| Important Notes | May cause dizziness; use caution when driving or operating machinery. Consult a doctor if you have heart problems. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Promethazine, Metoclopramide, Dimenhydrinate, Prochlorperazine |
Ondansetron Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Promethazine (Phenergan) | H1 receptor antagonist | May cause drowsiness. |
| Metoclopramide (Reglan) | Dopamine antagonist and prokinetic agent | Can increase stomach contractions. |
| Dimenhydrinate (Dramamine) | Antihistamine | Commonly used for motion sickness. |
| Prochlorperazine (Compazine) | Dopamine antagonist | May cause extrapyramidal symptoms. |
Ondansetron Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Serotonin syndrome (if taken with other serotonergic drugs) |
| Constipation | Irregular heartbeats (QT prolongation) |
| Diarrhea | Blurred vision |
| Dizziness | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Fatigue | Seizures (rare) |
Ondansetron Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Chemotherapy-Induced Nausea and Vomiting | 8 mg | 8 mg every 8 hours or 16 mg once daily | Administer 30 minutes before chemotherapy. |
| Postoperative Nausea and Vomiting | 4 mg | 4 mg every 8 hours | Administer before anesthesia induction. |
| Radiation-Induced Nausea and Vomiting | 8 mg | 8 mg every 8 hours | Administer 1-2 hours before radiation. |
Ondansetron Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $15 |
| Without Insurance (U.S.) | $25 – $60 |
| From CPS | $60 |
