Ongentys (Opicapone)

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Description

General Medication Fact Sheet for Ongentys

Field Information
Medication Name Ongentys
Generic Name Opicapone
Purpose Used as an add-on treatment to levodopa/carbidopa in patients with Parkinson’s disease experiencing “off” episodes.
Mechanism of Action Selective and reversible catechol-O-methyltransferase (COMT) inhibitor, which helps to prevent the breakdown of levodopa, thereby prolonging its effect.
Dosage Forms Oral capsules
Available Strengths 50 mg
Dosage Frequency Once daily at bedtime.
Common Side Effects Dyskinesia, constipation, blood creatine kinase increased, hypotension, weight decrease.
Serious Side Effects Hallucinations, psychotic behavior, impulse control disorders.
Drug Interactions COMT inhibitors, MAO inhibitors, drugs metabolized by COMT (e.g., isoproterenol, epinephrine).
Important Notes Take at bedtime and at least one hour before or after levodopa/carbidopa. Monitor for dyskinesias, hallucinations, and impulse control disorders.
Storage Store at room temperature between 68°F to 77°F (20°C to 25°C). Protect from moisture.
Missed Dose If you miss a dose, take it as soon as you remember that day. If you don’t remember until the next day, skip the missed dose and continue with your regular schedule. Do not double your dose.
Alternatives Entacapone (Comtan), Tolcapone (Tasmar), Istradefylline (Nourianz)

Ongentys Alternatives

Medication Mechanism of Action Notes
Entacapone (Comtan) COMT inhibitor Shorter duration of action compared to opicapone; needs to be taken with each dose of levodopa/carbidopa.
Tolcapone (Tasmar) COMT inhibitor More potent than Entacapone but carries a risk of liver toxicity, requiring regular liver function monitoring.
Istradefylline (Nourianz) Adenosine A2A receptor antagonist Works through a different mechanism to reduce “off” episodes in Parkinson’s disease.

Ongentys Side Effects

Common Side Effects Serious Side Effects
Dyskinesia Hallucinations
Constipation Psychotic behavior
Blood creatine kinase increased Impulse control disorders (e.g., compulsive gambling, increased sexual urges)
Hypotension Neuroleptic Malignant Syndrome (NMS)
Weight decrease Rhabdomyolysis

Ongentys Dosage Guide

Condition Starting Dose Maintenance Dose Administration Notes
Parkinson’s Disease (with “off” episodes) 50 mg 50 mg once daily Take at bedtime, at least one hour before or after levodopa/carbidopa.

Ongentys Price With And Without Insurance

Purchase Context Estimated Price
With Insurance $500
Without Insurance (U.S.) $1200
From Canada $900
Why Americans Buy Ongentys from Canada Pharmacy Store?

Why Americans Buy Ongentys from Canada Pharmacy Store?

Americans have trouble affording Ongentys due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
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Big Savings on U.S. Medications
Our customers save up to 80% on their Ongentys prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
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How to Order Ongentys Online

How to Order Ongentys Online

Step 1

Select Your Prescribed Ongentys Dosage

Choose the strength and quantity as directed by your healthcare provider and add it to your cart.

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Step 2

Proceed Through Secure Checkout

Follow the steps to complete your order and provide necessary shipping and payment details.

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Step 3

Upload Your Ongentys Prescription

Submit a prescription from a licensed U.S. healthcare provider that matches your order.

At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.

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Our Guarantee When You Buy Ongentys Through Canada Pharmacy Store

At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.

The Ongentys you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Ongentys at a lower price, simply place your order above or give us a call at 1-888-903-2240